Leber congenital amaurosis/early-onset severe retinal dystrophy: clinical features, molecular genetics and therapeutic interventions

N Kumaran, AT Moore, RG Weleber… - British journal of …, 2017 - bjo.bmj.com
Leber congenital amaurosis (LCA) and early-onset severe retinal dystrophy (EOSRD) are
both genetically and phenotypically heterogeneous, and characterised clinically by severe …

[图书][B] The neural bases of multisensory processes

MM Murray, MT Wallace - 2011 - taylorfrancis.com
It has become accepted in the neuroscience community that perception and performance
are quintessentially multisensory by nature. Using the full palette of modern brain imaging …

Compensatory plasticity and cross-modal reorganization following early visual deprivation

R Kupers, M Ptito - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
For human and non-human primates, vision is one of the most privileged sensory channels
used to interact with the environment. The importance of vision is strongly embedded in the …

Functional connectivity of visual cortex in the blind follows retinotopic organization principles

E Striem-Amit, S Ovadia-Caro, A Caramazza… - Brain, 2015 - academic.oup.com
Is visual input during critical periods of development crucial for the emergence of the
fundamental topographical mapping of the visual cortex? And would this structure be …

Thick visual cortex in the early blind

J Jiang, W Zhu, F Shi, Y Liu, J Li, W Qin… - Journal of …, 2009 - Soc Neuroscience
We investigated the key neurodevelopmental factors that determine cortical thickness,
namely synaptogenesis and regression, by analyzing the thickness of the visual cortex in …

Alterations of the visual pathways in congenital blindness

M Ptito, FCG Schneider, OB Paulson… - Experimental brain …, 2008 - Springer
We used whole brain MRI voxel-based morphometry (VBM) to study the anatomical
organization of the visual system in congenitally blind (CB) adults. Eleven CB without a …

Morphological alterations in the congenital blind based on the analysis of cortical thickness and surface area

HJ Park, JD Lee, EY Kim, B Park, MK Oh, SC Lee… - Neuroimage, 2009 - Elsevier
To explore the morphological aspects of the functional reorganization of the blind's visual
cortex, we analyzed the regional cortical thickness and cortical surface area in the …

Categorical representation from sound and sight in the ventral occipito-temporal cortex of sighted and blind

S Mattioni, M Rezk, C Battal, R Bottini… - elife, 2020 - elifesciences.org
Is vision necessary for the development of the categorical organization of the Ventral
Occipito-Temporal Cortex (VOTC)? We used fMRI to characterize VOTC responses to eight …

Altered anatomical network in early blindness revealed by diffusion tensor tractography

N Shu, Y Liu, J Li, Y Li, C Yu, T Jiang - PloS one, 2009 - journals.plos.org
The topological architecture of the cerebral anatomical network reflects the structural
organization of the human brain. Recently, topological measures based on graph theory …

Cortical maps and white matter tracts following long period of visual deprivation and retinal image restoration

N Levin, SO Dumoulin, J Winawer, RF Dougherty… - Neuron, 2010 - cell.com
Abnormal visual input during development has dramatic effects on the visual system. How
does the adult visual system respond when input is corrected? MM lost his left eye and …