Inflammation induced by platelet-activating viperid snake venoms: perspectives on thromboinflammation

C Teixeira, CM Fernandes, E Leiguez… - Frontiers in …, 2019 - frontiersin.org
Envenomation by viperid snakes is characterized by systemic thrombotic syndrome and
prominent local inflammation. To date, the mechanisms underlying inflammation and blood …

[HTML][HTML] Polymorphonuclear neutrophil leukocytes in snakebite envenoming

JP Zuliani, AM Soares, JM Gutiérrez - Toxicon, 2020 - Elsevier
Polymorphonuclear neutrophils are the most abundant leukocytes in the blood and
constitute key components of the innate immunity. Upon infection or tissue damage …

Immunological responses to envenomation

RYM Ryan, J Seymour, A Loukas, JA Lopez… - Frontiers in …, 2021 - frontiersin.org
Venoms are complex mixtures of toxic compounds delivered by bite or sting. In humans, the
consequences of envenomation range from self-limiting to lethal. Critical host defence …

[HTML][HTML] Dynamics of action of a Lys-49 and an Asp-49 PLA2s on inflammasome NLRP3 activation in murine macrophages

CN Boeno, MV Paloschi, JA Lopes, MDS Silva… - International …, 2022 - Elsevier
Abstract Phospholipases A 2 (PLA 2 s) are proteins found in snake venoms with hemolytic,
anticoagulant, myotoxic, edematogenic, bactericidal and inflammatory actions. In Bothrops …

Alarmins and inflammatory aspects related to snakebite envenomation

JP Zuliani - Toxicon, 2023 - Elsevier
Snakebite envenoming is characterized by the injection of a mixture of proteins/toxins
present in venom following the bite of a venomous snake. The toxins have potent bioactivity …

Effect of animal venom toxins on the main links of the homeostasis of mammals

R Matkivska, I Samborska… - Biomedical …, 2023 - spandidos-publications.com
The human body is affected by environmental factors. The dynamic balance between the
organism and its environment results from the influence of natural, anthropogenic and social …

[HTML][HTML] Effect of L-amino acid oxidase from Calloselasma rhodosthoma snake venom on human neutrophils

AS Pontes, SS Setúbal, CV Xavier, F Lacouth-Silva… - Toxicon, 2014 - Elsevier
The in vitro effects of LAAO, an l-amino acid oxidase isolated from Calloselasma
rhodosthoma snake venom, on isolated human neutrophil function were investigated. LAAO …

Activation of J77A.1 Macrophages by Three Phospholipases A2 Isolated from Bothrops atrox Snake Venom

JL Furtado, GA Oliveira, AS Pontes… - BioMed Research …, 2014 - Wiley Online Library
In the present study, we investigated the in vitro effects of two basic myotoxic
phospholipases A2 (PLA2), BaTX‐I, a catalytically inactive Lys‐49 variant, and BaTX‐II, a …

[HTML][HTML] Effect of Bothrops bilineata snake venom on neutrophil function

S da Silva Setubal, AS Pontes, NM Nery, JSF Bastos… - Toxicon, 2013 - Elsevier
The aim of the study was to evaluate the in vitro effects of Bothrops bilineata crude venom
(BbV) on isolated human neutrophil function. We proved that BbV isn't toxic towards human …

Light Emitting Diode Photobiomodulation Enhances Oxidative Redox Capacity in Murine Macrophages Stimulated with Bothrops jararacussu Venom and Isolated …

VP Dos Reis, S da Silva Setúbal… - BioMed Research …, 2022 - Wiley Online Library
Photobiomodulation therapy associated with conventional antivenom treatment has been
shown to be effective in reducing the local effects caused by bothropic venoms in preclinical …