The prefrontal cortex, pathological anxiety, and anxiety disorders
MM Kenwood, NH Kalin, H Barbas - Neuropsychopharmacology, 2022 - nature.com
Anxiety is experienced in response to threats that are distal or uncertain, involving changes
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …
The nature and neurobiology of fear and anxiety: State of the science and opportunities for accelerating discovery
Fear and anxiety play a central role in mammalian life, and there is considerable interest in
clarifying their nature, identifying their biological underpinnings, and determining their …
clarifying their nature, identifying their biological underpinnings, and determining their …
Viral tunes: changes in musical behaviours and interest in coronamusic predict socio-emotional coping during COVID-19 lockdown
Beyond immediate health risks, the COVID-19 pandemic poses a variety of stressors, which
may require expensive or unavailable strategies during a pandemic (eg, therapy …
may require expensive or unavailable strategies during a pandemic (eg, therapy …
Understanding anxiety symptoms as aberrant defensive responding along the threat imminence continuum
R Abend - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Threat-anticipatory defensive responses have evolved to promote survival in a dynamic
world. While inherently adaptive, aberrant expression of defensive responses to potential …
world. While inherently adaptive, aberrant expression of defensive responses to potential …
Pathological fear, anxiety and negative affect exhibit distinct neurostructural signatures: evidence from psychiatric neuroimaging meta-analysis
Internalizing disorders encompass anxiety, fear and depressive disorders, which exhibit
overlap at both conceptual and symptom levels. Given that a neurobiological evaluation is …
overlap at both conceptual and symptom levels. Given that a neurobiological evaluation is …
Robust BOLD responses to faces but not to conditioned threat: challenging the amygdala's reputation in human fear and extinction learning
Most of our knowledge about human emotional memory comes from animal research. Based
on this work, the amygdala is often labeled the brain's “fear center”, but it is unclear to what …
on this work, the amygdala is often labeled the brain's “fear center”, but it is unclear to what …
A neural signature for the subjective experience of threat anticipation under uncertainty
Uncertainty about potential future threats and the associated anxious anticipation represents
a key feature of anxiety. However, the neural systems that underlie the subjective …
a key feature of anxiety. However, the neural systems that underlie the subjective …
Impact of stress on brain morphology: Insights into structural biomarkers of stress-related disorders
Exposure to acute and chronic stress has a broad range of structural effects on the brain.
The brain areas commonly targeted in the stress response models include the …
The brain areas commonly targeted in the stress response models include the …
[HTML][HTML] Are fear and anxiety truly distinct?
L Daniel-Watanabe, PC Fletcher - Biological psychiatry global open science, 2022 - Elsevier
Fear and anxiety are largely seen as separate entities, a distinction that inspires and shapes
basic and clinical research. Evidence for this distinction has a rich translational base and …
basic and clinical research. Evidence for this distinction has a rich translational base and …
[HTML][HTML] How stress hormones shape memories of fear and anxiety in humans
Stress hormones influence the processing of fear, anxiety, and related memory mechanisms.
For example, they modulate consolidation and retrieval processes associated with …
For example, they modulate consolidation and retrieval processes associated with …