Expansion microscopy (ExM) is a newly developed super-resolution technique, allowing
visualization of biological targets at nanoscale resolution on conventional fluorescence …

Fluorescence microscopy has become a ubiquitous method to observe the location of
specific molecular components within cells. However, the resolution of light microscopy is …

Expansion microscopy enables nanoimaging with conventional microscopes by physically
and isotropically magnifying preserved biological specimens embedded in a crosslinked …

Expansion microscopy (ExM) is a powerful technique to overcome the diffraction limit of light
microscopy that can be applied in both tissues and cells. In ExM, samples are embedded in …

Expansion microscopy (ExM) allows super-resolution imaging on conventional fluorescence
microscopes, but has been limited to proteins and nucleic acids. Here we develop click-ExM …

Resolving the distribution of specific proteins at the nanoscale in the ultrastructural context of
the cell is a major challenge in fluorescence microscopy. We report the discovery of a new …

Super-resolution microscopy is a series of imaging techniques that bypass the diffraction
limit of resolution. Since the 1990s, optical approaches, such as single-molecular …

Strategies to visualize cellular membranes with light microscopy are restricted by the
diffraction limit of light, which far exceeds the dimensions of lipid bilayers. Here, we describe …

Expansion microscopy (ExM) is in increasingly widespread use throughout biology because
its isotropic physical magnification enables nanoimaging on conventional microscopes. To …

We recently developed expansion microscopy (ExM), which achieves nanoscale-precise
imaging of specimens at~ 70 nm resolution (with~ 4.5 x linear expansion) by isotropic …