Diosgenin: an updated pharmacological review and therapeutic perspectives

P Semwal, S Painuli, T Abu-Izneid… - Oxidative medicine …, 2022 - Wiley Online Library
Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain
a lot of diosgenin, a steroidal sapogenin. This bioactive phytochemical has shown high …

Examining later-in-life health risks associated with sport-related concussion and repetitive head impacts: a systematic review of case-control and cohort studies

GL Iverson, RJ Castellani, JD Cassidy… - British journal of sports …, 2023 - bjsm.bmj.com
Objective Concern exists about possible problems with later-in-life brain health, such as
cognitive impairment, mental health problems and neurological diseases, in former athletes …

[HTML][HTML] Recent advances in the therapeutic potential of emodin for human health

J Sharifi-Rad, J Herrera-Bravo, S Kamiloglu… - Biomedicine & …, 2022 - Elsevier
Abstract Emodin (1, 3, 8-trihydroxy-6-methylanthraquinone) is a bioactive compound, a
natural anthraquinone aglycone, present mainly in herbaceous species of the families …

The role of potential oxidative biomarkers in the prognosis of acute ischemic stroke and the exploration of antioxidants as possible preventive and treatment options

FZ Kamal, R Lefter, H Jaber, IM Balmus… - International Journal of …, 2023 - mdpi.com
Ischemic strokes occur when the blood supply to a part of the brain is interrupted or reduced
due to arterial blockage, and it often leads to damage to brain cells or death. According to a …

The role of microglial exosomes and miR-124-3p in neuroinflammation and neuronal repair after traumatic brain injury

I Mavroudis, IM Balmus, A Ciobica, MN Nicoara… - Life, 2023 - mdpi.com
(1) Background: In this study, we aimed to explore the regulatory mechanism of miR-124-3p
microglial exosomes, as they were previously reported to modulate neuroinflammation and …

The evolving role of extracellular vesicles (exosomes) as biomarkers in traumatic brain injury: Clinical perspectives and therapeutic implications

NA Khan, M Asim, A El-Menyar, KH Biswas… - Frontiers in Aging …, 2022 - frontiersin.org
Developing effective disease-modifying therapies for neurodegenerative diseases (NDs)
requires reliable diagnostic, disease activity, and progression indicators. While desirable …

Concussion is a temporary disability: rethinking mild traumatic brain injury in sports medicine

ZW Bevilacqua - Frontiers in neurology, 2024 - frontiersin.org
© 2024 Bevilacqua. This is an open-access article distributed under the terms of the
Creative Commons Attribution License (CC BY). The use, distribution and reproduction in …

A Systematic Review and Meta-Analysis of the Grey Matter Volumetric Changes in Mild Traumatic Brain Injuries

I Mavroudis, S Chatzikonstantinou, A Ciobica… - Applied Sciences, 2022 - mdpi.com
Traumatic brain injury (TBI) is currently a problematic issue of public health due to its
frequency, and many of the mild cases often remain undiagnosed despite the possible …

Identifying delay in glymphatic clearance of labeled protons post-acute head trauma utilizing 3D ASL MRI (arterial spin labeling): A pilot study

CR Joseph, JK Lim, BN Grohol, M Zivcevska… - Scientific Reports, 2024 - nature.com
This study correlated mild traumatic brain injury (mTBI) cognitive changes with ASL-MRI
glymphatic clearance rates (GCRs) and recovery with GCR improvement. mTBI disrupts the …

Emerging frontiers in Chronic Traumatic Encephalopathy: Early diagnosis and implications for neurotherapeutic interventions

W Blanks, M Hanshaw, DA Perez-Chadid… - Expert Review of …, 2024 - Taylor & Francis
ABSTRACT Introduction Chronic Traumatic Encephalopathy (CTE) is a neurodegenerative
disorder associated with repetitive head trauma. Historically, the diagnosis has been …