Ischemic stroke generates an immune response that contributes to neuronal loss as well as
tissue repair. This is a complex process involving a range of cell types and effector …

The immune response to acute cerebral ischemia is a major factor in stroke pathobiology
and outcome. While the immune response starts locally in occluded and hypoperfused …

Animals constantly receive various sensory stimuli, such as odours, sounds, light and touch,
from the surrounding environment. These sensory inputs are essential for animals to search …

The mechanism and long-term consequences of early blood–brain barrier (BBB) disruption
after cerebral ischaemic/reperfusion (I/R) injury are poorly understood. Here we discover …

Matrix metalloproteinases are versatile endopeptidases with many different functions in the
body in health and disease. In the brain, matrix metalloproteinases are critical for tissue …

Sepsis-associated encephalopathy (SAE) is a cognitive impairment associated with sepsis
that occurs in the absence of direct infection in the central nervous system or structural brain …

The fast and accurate assessment of cerebral perfusion is fundamental for the diagnosis and
successful treatment of stroke patients. Magnetic particle imaging (MPI) is a new radiation …

Major depression represents a complex and prevalent psychological disease that is
characterized by persistent depressed mood, impaired cognitive function and complicated …

Brain edema is one of the most devastating consequences of ischemic stroke. Malignant
cerebral edema is the main reason accounting for the high mortality rate of large …

Blood-brain barrier (BBB) injury critically exacerbates the poor prognosis of patients with
subarachnoid hemorrhage (SAH). The massively increased matrix metalloproteinases 9 …