Apoptosis or programmed cell death is natural way of removing aged cells from the body.
Most of the anti-cancer therapies trigger apoptosis induction and related cell death networks …

Breast cancer is the cancer with the highest prevalence in women and is the number‐one
cause of cancer mortality worldwide. Cell transduction is a fundamental process in the …

The members of the Bcl-2 family are the central regulators of various cell death modalities.
Some of these proteins contribute to apoptosis, while others counteract this type of …

Prostate cancer is one of the most common types of cancer affecting men worldwide;
however, its etiology and pathological mechanisms remain poorly understood. Mechanical …

Breast cancer is the second leading cause of cancer related deaths among women aged 40–
55 in the United States and currently affects more than one in ten women worldwide. It is …

The ERK 1/2 signalling pathway is best known for its role in connecting activated growth
factor receptors to changes in gene expression due to activated ERK 1/2 entering the …

Purpose Triple-negative breast cancer (TNBC), an aggressive breast cancer subtype, is
genetically heterogeneous which challenges the identification of clinically effective …

Regulation of both the extrinsic and the mitochondria-dependent intrinsic apoptotic
pathways plays a key role in the development of the hematopoietic system, for sustaining …

Early embryonic arrest and fragmentation (EEAF) is a common phenomenon leading to
female infertility, but the genetic determinants remain largely unknown. The Moloney …

Background Asprosin, a newly discovered adipokine, is a C-terminal cleavage product of
profibrillin. Asprosin has been reported to participate in lipid metabolism and cardiovascular …