Antibodies and antibody derivatives constitute 20% of biopharmaceutical products currently
in development, and despite early failures of murine products, chimeric and humanized …

Many successful, recent therapies for life-threatening diseases such as cancer and
rheumatoid arthritis are based on the recognition between native or genetically engineered …

Histochemistry deals with the activities of chemical components in cells, and
immunohistochemistry addresses the function of cell types in tissue or organs, such as those …

Abstract Sperm protein 17 (Sp17) is an antigenic protein highly expressed in spermatozoa.
Sp17 expression was demonstrated recently in multiple myeloma, suggesting that it may be …

In the early eighties it was realized that the ultimate vaccine would be a synthetic peptide.
Major efforts were put into the development of a synthetic vaccine for foot-and-mouth …

We prepared fusogenic liposomes by fusing conventional liposomes with an ultra-violet
inactivated Sendai virus. Fusogenic liposomes can deliver encapsulated contents into the …

The rapidly increasing implementation of antibodies in therapeutic and diagnostic
applications has necessitated the development of antibody production and purification …

Cytotoxic T lymphocyte (CTL)-based cancer immunotherapies have shown great promise for
inducing clinical regressions by targeting tumor-associated antigens (TAA). To expand the …

1. ABSTRACT Thomsen-Friedenreich antigen (TF-Ag) is the disaccharide (Gal beta1-3
GalNAc alpha), which is also known as the core 1 structure. The presence of this …

Ribosome display is a polymerase chain reaction-based invitro display technology that is
well suited to the selection and evolution of high affinity antibodies. Both eukaryotic and …