[HTML][HTML] Recent advances in understanding Streptomyces

KF Chater - F1000Research, 2016 - ncbi.nlm.nih.gov
Abstract About 2,500 papers dated 2014–2016 were recovered by searching the PubMed
database for Streptomyces, which are the richest known source of antibiotics. This review …

c-di-GMP signalling and the regulation of developmental transitions in streptomycetes

MJ Bush, N Tschowri, S Schlimpert, K Flärdh… - Nature Reviews …, 2015 - nature.com
The complex life cycle of streptomycetes involves two distinct filamentous cell forms: the
growing (or vegetative) hyphae and the reproductive (or aerial) hyphae, which differentiate …

Specialised metabolites regulating antibiotic biosynthesis in Streptomyces spp.

G Niu, KF Chater, Y Tian, J Zhang… - FEMS Microbiology …, 2016 - academic.oup.com
Streptomyces bacteria are the major source of antibiotics and other secondary metabolites.
Various environmental and physiological conditions affect the onset and level of production …

c-di-GMP arms an anti-σ to control progression of multicellular differentiation in Streptomyces

KA Gallagher, MA Schumacher, MJ Bush, MJ Bibb… - Molecular Cell, 2020 - cell.com
Streptomyces are our primary source of antibiotics, produced concomitantly with the
transition from vegetative growth to sporulation in a complex developmental life cycle. We …

Two dynamin-like proteins stabilize FtsZ rings during Streptomyces sporulation

S Schlimpert, S Wasserstrom… - Proceedings of the …, 2017 - National Acad Sciences
During sporulation, the filamentous bacteria Streptomyces undergo a massive cell division
event in which the synthesis of ladders of sporulation septa convert multigenomic hyphae …

Genome-wide chromatin immunoprecipitation sequencing analysis shows that WhiB is a transcription factor that cocontrols its regulon with WhiA to initiate …

MJ Bush, G Chandra, MJ Bibb, KC Findlay, MJ Buttner - MBio, 2016 - Am Soc Microbiol
WhiB is the founding member of a family of proteins (the W hi Bl ike [Wbl] family) that carry a
[4Fe-4S] iron-sulfur cluster and play key roles in diverse aspects of the biology of …

Development of Next Generation Synthetic Biology Tools for Use in Streptomyces venezuelae

RM Phelan, D Sachs, SJ Petkiewicz… - ACS synthetic …, 2017 - ACS Publications
Streptomyces have a rich history as producers of important natural products and this genus
of bacteria has recently garnered attention for its potential applications in the broader …

ParA and ParB coordinate chromosome segregation with cell elongation and division during Streptomyces sporulation

M Donczew, P Mackiewicz, A Wróbel… - Open …, 2016 - royalsocietypublishing.org
In unicellular bacteria, the ParA and ParB proteins segregate chromosomes and coordinate
this process with cell division and chromosome replication. During sporulation of mycelial …

Genetic network architecture and environmental cues drive spatial organization of phenotypic division of labor in Streptomyces coelicolor

VM Zacharia, Y Ra, C Sue, E Alcala, JN Reaso… - MBio, 2021 - Am Soc Microbiol
ABSTRACT A number of bacteria are known to differentiate into cells with distinct phenotypic
traits during processes such as biofilm formation or the development of reproductive …

Hyphal compartmentalization and sporulation in Streptomyces require the conserved cell division protein SepX

MJ Bush, KA Gallagher, G Chandra, KC Findlay… - Nature …, 2022 - nature.com
Filamentous actinobacteria such as Streptomyces undergo two distinct modes of cell
division, leading to partitioning of growing hyphae into multicellular compartments via cross …