Neuroinflammatory markers: key indicators in the pathology of neurodegenerative diseases

A Rauf, H Badoni, T Abu-Izneid, A Olatunde… - Molecules, 2022 - mdpi.com
Neuroinflammation, a protective response of the central nervous system (CNS), is
associated with the pathogenesis of neurodegenerative diseases. The CNS is composed of …

Role of inflammatory molecules in the Alzheimer's disease progression and diagnosis

E Bagyinszky, V Van Giau, K Shim, K Suk… - Journal of the …, 2017 - Elsevier
Alzheimer's disease (AD) is a complex disorder and the most common form of
neurodegenerative dementia. Several genetic, environmental, and physiological factors …

Neutralization of IL‐17 rescues amyloid‐β‐induced neuroinflammation and memory impairment

C Cristiano, F Volpicelli, P Lippiello… - British journal of …, 2019 - Wiley Online Library
Background and purpose Alzheimer's disease (AD) is a common neurodegenerative
disease characterized by a neuroinflammatory state, and to date, there is no cure and its …

The relationship between chronic immune response and neurodegenerative damage in long COVID-19

JP Elizalde-Díaz, CL Miranda-Narváez… - Frontiers in …, 2022 - frontiersin.org
In the past two years, the world has faced the pandemic caused by the severe acute
respiratory syndrome 2 coronavirus (SARS-CoV-2), which by August of 2022 has infected …

Acute hypoxia induced an imbalanced M1/M2 activation of microglia through NF-κB signaling in Alzheimer's disease mice and wild-type littermates

F Zhang, R Zhong, S Li, Z Fu, C Cheng… - Frontiers in aging …, 2017 - frontiersin.org
Alzheimer's disease (AD) is the most common neurodegenerative disease mainly caused by
abnormal tau phosphorylation, amyloid β (Aβ) deposition and neuroinflammation. As an …

Systemic and CNS inflammation crosstalk: implications for Alzheimer's disease

E Paouri, S Georgopoulos - Current Alzheimer Research, 2019 - ingentaconnect.com
After years of failed therapeutic attempts targeting beta-amyloid (Aβ) in AD, there is now
increasing evidence suggesting that inflammation holds a pivotal role in AD pathogenesis …

[HTML][HTML] Mechanistic role of boswellic acids in Alzheimer's disease: Emphasis on anti-inflammatory properties

A Siddiqui, Z Shah, RN Jahan, I Othman… - Biomedicine & …, 2021 - Elsevier
The resin/gum of Boswellia species belonging to the family of Burseraceae is a naturally
occurring mixture of bioactive compounds, which was traditionally used as a folk medicine to …

T lymphocytes and inflammatory mediators in the interplay between brain and blood in Alzheimer's disease: potential pools of new biomarkers

A Mietelska-Porowska, U Wojda - Journal of immunology …, 2017 - Wiley Online Library
Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the main cause of
dementia. The disease is among the leading medical concerns of the modern world …

Differential compartmentalization of myeloid cell phenotypes and responses towards the CNS in Alzheimer's disease

C Fernández Zapata, G Giacomello, EJ Spruth… - Nature …, 2022 - nature.com
Myeloid cells are suggested as an important player in Alzheimer´ s disease (AD). However,
its continuum of phenotypic and functional changes across different body compartments and …

Chemokines as new inflammatory players in the pathogenesis of epilepsy

C Cerri, M Caleo, Y Bozzi - Epilepsy Research, 2017 - Elsevier
A large series of clinical and experimental studies supports a link between inflammation and
epilepsy, indicating that inflammatory processes within the brain are important contributors …