Natural Compounds: A Hopeful Promise as an Antibiofilm Agent Against Candida Species

A Shariati, M Didehdar, S Razavi, M Heidary… - Frontiers in …, 2022 - frontiersin.org
The biofilm communities of Candida are resistant to various antifungal treatments. The ability
of Candida to form biofilms on abiotic and biotic surfaces is considered one of the most …

Novel avenues for identification of new antifungal drugs and current challenges

J Jampilek - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
Introduction Some of the fungi have become pathogenic to humans, and these opportunistic
pathogens are able to cause severe systemic mycoses. Areas covered The number of …

Antifungal mechanism of 1-nonanol against Aspergillus flavus growth revealed by metabolomic analyses

SB Zhang, YL Qin, SF Li, YY Lv, HC Zhai, YS Hu… - Applied microbiology …, 2021 - Springer
Chemical control of fungal spoilage of postharvest cereal grains is an important strategy for
the management of grain storage. Here, the potential antifungal activity of 1-nonanol, a main …

Antifungal, Antioxidant and Antibiofilm Activities of Essential Oils of Cymbopogon spp.

W Rhimi, MA Mohammed, AAK Zarea, G Greco… - Antibiotics, 2022 - mdpi.com
Essential oils (EOs) of Cymbopogon citratus and Cymbopogon proximus are known as
sources of monoterpenes and sesquiterpenoids, although their biological activities have not …

Biochemical and metabolomic insights into antifungal mechanism of berberine against Candida glabrata

P Gupta, H Gupta, S Tripathi, KM Poluri - Applied Microbiology and …, 2023 - Springer
An unprecedented expansion of antifungal therapy failure incidences in healthcare settings
of Candida glabrata is the matter of global concern that needs to be addressed efficiently …

Geraniol inhibits biofilm formation of methicillin-resistant Staphylococcus aureus and increase the therapeutic effect of vancomycin in vivo

K Gu, P Ouyang, Y Hong, Y Dai, T Tang, C He… - Frontiers in …, 2022 - frontiersin.org
Methicillin-resistant Staphylococcus aureus (MRSA) is among the common drug resistant
bacteria, which has gained worldwide attention due to its high drug resistance and infection …

Deciphering the Mechanism of MRSA Targeting Copper(II) Complexes of NN2 Pincer-Type Ligands

A Das, R Sangavi, S Gowrishankar, R Kumar… - Inorganic …, 2023 - ACS Publications
WHO lists AMR as one of the top ten global public health issues. Therefore, constant effort is
needed to develop more efficient antimicrobial drugs. As a result, earth-abundant transition …

Azole-Based Compounds That Are Active against Candida Biofilm: In Vitro, In Vivo and In Silico Studies

S Carradori, A Ammazzalorso, B De Filippis, AF Şahin… - Antibiotics, 2022 - mdpi.com
Fungal pathogens, including Candida spp., Aspergillus spp. and dermatophytes, cause
more than a billion human infections every year. A large library of imidazole-and triazole …

Antipruritic effects of geraniol on acute and chronic itch via modulating spinal GABA/GRPR signaling

Y Yang, L Du, J Zhu, T Yi, Y Yang, Z Qiao, Q Maoying… - Phytomedicine, 2023 - Elsevier
Background and purpose Itch (pruritus) is a common unpleasant feeling, often accompanied
by the urge of scratching the skin. It is the main symptom of many systemic and skin …

Assessing the eradication potential of fungal biofilms using acacia gum/PVA nanofibers functionalized with geraniol-β cyclodextrin inclusion complex

P Gupta, P Mishra, N Verma, J Alhariry, C Kumar… - Journal of Drug Delivery …, 2024 - Elsevier
The world is witnessing severe fungal co-infections with incidences of antifungal resistance
and increased morbidity/mortality. The present study is focused on fabricating geraniol …