A marked decrease in malaria-related deaths worldwide has been attributed to the
administration of effective antimalarials against Plasmodium falciparum, in particular …

Antimalarial drug resistance, in particular resistance to Plasmodium falciparum, challenges
the treatment and control of malaria. In this Review, we summarise evolving patterns of …

Antimalarial drugs are key tools for the control and elimination of malaria. Recent decreases
in the global malaria burden are likely due, in part, to the deployment of artemisinin-based …

Antimalarial chemotherapy, globally reliant on artemisinin-based combination therapies
(ACTs), is threatened by the spread of drug resistance in Plasmodium falciparum parasites …

Despite great international efforts, malaria still inflicts an enormous toll on human lives,
especially in Africa. Throughout history, antimalarial medicines have been one of the most …

Malaria is a major public health burden throughout the world. Resistance to the antimalarial
drugs has increased the mortality and morbidity rate that is achieved so far through the …

Plasmodium falciparum resistance to chloroquine, the former gold standard antimalarial
drug, is mediated primarily by mutant forms of the chloroquine resistance transporter …

The role of protein phosphorylation in the life cycle of malaria parasites is slowly emerging.
Here we combine global phospho-proteomic analysis with kinome-wide reverse genetics to …

Resistance to antimalarial drugs has often threatened malaria elimination efforts and
historically has led to the short-term resurgence of malaria incidences and deaths. With …

The global dissemination of drug-resistant Plasmodium falciparum is spurring intense efforts
to implement artemisinin (ART)–based combination therapies for malaria, including …