Metabolic profiles of cancer cells

JL Griffin, JP Shockcor - Nature reviews cancer, 2004 - nature.com
In the post-genomic era, several profiling tools have been developed to provide a more
comprehensive picture of tumour development and progression. The global analysis of …

In-cell NMR: Why and how?

FX Theillet, E Luchinat - Progress in Nuclear Magnetic Resonance …, 2022 - Elsevier
NMR spectroscopy has been applied to cells and tissues analysis since its beginnings, as
early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …

Metabonomics: NMR spectroscopy and pattern recognition analysis of body fluids and tissues for characterisation of xenobiotic toxicity and disease diagnosis

JL Griffin - Current opinion in chemical biology, 2003 - Elsevier
Global profiling tools are required to fully understand the impact of genetic modifications and
toxicological interventions on the network of transcripts, proteins and metabolites found …

Solvent signal suppression in NMR

G Zheng, WS Price - Progress in Nuclear Magnetic Resonance …, 2010 - Elsevier
In 1H Nuclear Magnetic Resonance (NMR) experiments (including biomolecular NMR and
in vivo Magnetic Resonance Spectroscopy (MRS)), solvents normally have significantly …

The Cinderella story of metabolic profiling: does metabolomics get to go to the functional genomics ball?

JL Griffin - … Transactions of the Royal Society B …, 2006 - royalsocietypublishing.org
To date most global approaches to functional genomics have centred on genomics,
transcriptomics and proteomics. However, since a number of high-profile publications …

HR MAS MR spectroscopy in metabolic characterization of cancer

S Moestue, B Sitter, T Frost Bathen… - Current topics in …, 2011 - ingentaconnect.com
One of the central hallmarks of cancer is the rapid and infinite cellular proliferation. In order
to cope with increased requirement for building blocks and energy, cancer cells develop …

Metabolomic profiling of human serum in lung cancer patients using liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry and gas …

Y Chen, Z Ma, A Li, H Li, B Wang, J Zhong… - Journal of cancer …, 2015 - Springer
Purpose Lung cancer is one of the most common causes of death from cancer. Serum
markers that enable diagnosis of the disease in the early stage have not been found …

Metabolic profiling of potential lung cancer biomarkers using bronchoalveolar lavage fluid and the integrated direct infusion/gas chromatography mass spectrometry …

B Callejon-Leblic, T Garcia-Barrera… - Journal of …, 2016 - Elsevier
Lung cancer is one of the ten most common causes of death worldwide, so that the search
for early diagnosis biomarkers is a very challenging task. Bronchoalveolar lavage fluid …

Biomarker identification and pathway analysis by serum metabolomics of lung cancer

Y Chen, Z Ma, L Min, H Li, B Wang… - BioMed research …, 2015 - Wiley Online Library
Lung cancer is one of the most common causes of cancer death, for which no validated
tumor biomarker is sufficiently accurate to be useful for diagnosis. Additionally, the metabolic …

High-resolution magic angle spinning (HR MAS) MR spectroscopy in metabolic characterization of human cancer

B Sitter, TF Bathen, MB Tessem… - Progress in nuclear …, 2009 - Elsevier
Cancer is a disease with high prevalence in western and industrialized countries. The
incidence of cancer has been increasing, while mortality has either been stable or …