The molecular biology of Bluetongue virus replication

A Patel, P Roy - Virus research, 2014 - Elsevier
The members of Orbivirus genus within the Reoviridae family are arthropod-borne viruses
which are responsible for high morbidity and mortality in ruminants. Bluetongue virus (BTV) …

Functional mapping of bluetongue virus proteins and their interactions with host proteins during virus replication

P Roy - Cell biochemistry and biophysics, 2008 - Springer
Bluetongue virus (BTV) is a double-stranded RNA (dsRNA) virus which is transmitted by
blood-feeding gnats to wild and domestic ruminants, causing high morbidity and often high …

Characterization of a second open reading frame in genome segment 10 of bluetongue virus

M Stewart, A Hardy, G Barry… - Journal of General …, 2015 - microbiologyresearch.org
Viruses have often evolved overlapping reading frames in order to maximize their coding
capacity. Until recently, the segmented dsRNA genome of viruses of the Orbivirus genus …

[HTML][HTML] Bluetongue: a review

A Sperlova, D Zendulkova - Veterinarni Medicina, 2011 - vetmed.agriculturejournals.cz
Bluetongue is a non-contagious disease of domestic and wild ruminants caused by a virus
within the Orbivirus genus of the family Reoviridae and transmitted by Culicoides biting …

Reassortment between two serologically unrelated bluetongue virus strains is flexible and can involve any genome segment

AE Shaw, M Ratinier, SF Nunes, K Nomikou… - Journal of …, 2013 - Am Soc Microbiol
Coinfection of a cell by two different strains of a segmented virus can give rise to a
“reassortant” with phenotypic characteristics that might differ from those of the parental …

Role of NS2 specific RNA binding and phosphorylation in liquid–liquid phase separation and virus assembly

SK Rahman, KK Ampah, P Roy - Nucleic acids research, 2022 - academic.oup.com
Liquid–liquid phase separation (LLPS) has assumed a prominent role in biological cell
systems, where it underpins the formation of subcellular compartments necessary for cell …

Bluetongue virus NS4 protein is an interferon antagonist and a determinant of virus virulence

M Ratinier, AE Shaw, G Barry, Q Gu… - Journal of …, 2016 - Am Soc Microbiol
Bluetongue virus (BTV) is the causative agent of bluetongue, a major infectious disease of
ruminants with serious consequences to both animal health and the economy. The clinical …

Interaction between Bluetongue virus outer capsid protein VP2 and vimentin is necessary for virus egress

B Bhattacharya, RJ Noad, P Roy - Virology journal, 2007 - Springer
Background The VP2 outer capsid protein Bluetongue Virus (BTV) is responsible for
receptor binding, haemagglutination and eliciting host-specific immunity. However, the …

Sequential packaging of RNA genomic segments during the assembly of Bluetongue virus

PY Sung, P Roy - Nucleic acids research, 2014 - academic.oup.com
Bluetongue virus (BTV), a member of the Orbivirus genus within the Reoviridae family, has a
genome of 10 double-stranded RNA segments, with three distinct size classes. Although the …

Bluetongue virus VP6 acts early in the replication cycle and can form the basis of chimeric virus formation

E Matsuo, P Roy - Journal of virology, 2009 - Am Soc Microbiol
ABSTRACT A minor core protein, VP6, of bluetongue virus (BTV) possesses nucleoside
triphosphatase, RNA binding, and helicase activities. Although the enzymatic functions of …