Chitosan as a polycationic non-viral vector for gene delivery has the advantage of being a
biocompatible and biodegradable polymer. However, without laborious chemical …

Introduction: The field of nanomedicine, utilizing nano-sized vehicles (nanoparticles and
nanofibers) for targeted local drug delivery, has a promising future. This is dependent on the …

The microbial cell membrane is affected by physicochemical parameters, such as
temperature and pH, but also by the specific growth rate of the host organism …

Photodynamic therapy (PDT) is an established noninvasive tumor treatment. The
hydrophobic natural occurring pigment hypericin shows a lot of attractive properties for the …

Antimicrobial strategies with high efficacy against bacterial infections are urgently needed.
The development of effective therapies to control bacterial infections is still a challenge …

(1) Background: Extracellular vesicles (EVs) are considered to be efficient nanocarriers for
improved drug delivery and can be derived from mammalian or plant cells. Cucumber …

The potent photodynamic properties of Hypericin (Hyp) elicit a range of light-dose-
dependent anti-tumor activities. However, its low water solubility hampers its broad …

Lung cancer is one of the most common causes for a high number of cancer related
mortalities worldwide. Therefore, it is important to improve the therapy by finding new targets …

Clinical success of effective gene therapy is mainly hampered by the insufficiency of safe
and efficient internalization of a transgene to the targeted cellular site. Therefore, the …

Parietin (PTN) is an anthraquinone with promising efficacy in the inhibition of cancer cell
proliferation and tumor growth. Due to its hydrophobicity, PTN is sparingly soluble under …