[HTML][HTML] Orthotopic and metastatic tumour models in preclinical cancer research
SM Stribbling, C Beach, AJ Ryan - Pharmacology & Therapeutics, 2024 - Elsevier
Mouse models of disease play a pivotal role at all stages of cancer drug development. Cell-
line derived subcutaneous tumour models are predominant in early drug discovery, but …
line derived subcutaneous tumour models are predominant in early drug discovery, but …
[HTML][HTML] Obesity and cancer stem cells: roles in cancer initiation, progression and therapy resistance
WJ Xie, J Li - World Journal of Stem Cells, 2023 - ncbi.nlm.nih.gov
Obesity, the global pandemic since industrialization, is the number one lifestyle-related risk
factor for premature death, which increases the incidence and mortality of various diseases …
factor for premature death, which increases the incidence and mortality of various diseases …
[HTML][HTML] A Landscape of Cancer Initiation and Cancer Stem Cells
M Seno - Cancers, 2025 - mdpi.com
Exposure to radiation and chemicals, oncogenic viruses, microbiomes, and inflammation are
the major events of cancer initiation. DNA damage and chromosomal aberrations are …
the major events of cancer initiation. DNA damage and chromosomal aberrations are …
On the Origin of Cancer
SM Afify, M Seno - Methods in Cancer Stem Cell Biology, 2023 - Springer
Cancer is a disease with a long history from prehistoric times that could be traced back to the
era of dinosaurs. In humans, cancer becomes prevalent much more than ever due to the …
era of dinosaurs. In humans, cancer becomes prevalent much more than ever due to the …