Environmental fate and ecotoxicological effects of antiretrovirals: a current global status and future perspectives

S Ncube, LM Madikizela, L Chimuka, MM Nindi - Water research, 2018 - Elsevier
The therapeutic efficacy of antiretroviral drugs as well as challenges and side effects against
the human immunodeficiency virus is well documented and reviewed. Evidence is available …

Casein kinase 1α mediates eryptosis: a review

A Tkachenko, A Onishchenko - Apoptosis, 2023 - Springer
Eryptosis is a coordinated non-lytic cell death of erythrocytes characterized by cell
shrinkage, cell membrane scrambling, Ca2+ influx, ceramide accumulation, oxidative stress …

Apoptosis and eryptosis: similarities and differences

A Tkachenko - Apoptosis, 2024 - Springer
Eryptosis is a regulated cell death (RCD) of mature erythrocytes initially described as a
counterpart of apoptosis for enucleated cells. However, over the recent years, a growing …

Eryptosis in health and disease: A paradigm shift towards understanding the (patho) physiological implications of programmed cell death of erythrocytes

SM Qadri, R Bissinger, Z Solh, PA Oldenborg - Blood reviews, 2017 - Elsevier
During the course of their natural ageing and upon injury, anucleate erythrocytes can
undergo an unconventional apoptosis-like cell death, termed eryptosis. Eryptotic …

Suicidal death of erythrocytes in cancer and its chemotherapy: A potential target in the treatment of tumor‐associated anemia

E Lang, R Bissinger, SM Qadri… - International Journal of …, 2017 - Wiley Online Library
In analogy to apoptosis of nucleated cells, erythrocytes may enter eryptosis characterized by
cell shrinkage and cell membrane scrambling. Eryptotic erythrocytes are rapidly cleared …

The antagonism of folate receptor by dolutegravir: developmental toxicity reduction by supplemental folic acid

RM Cabrera, JP Souder, JW Steele, L Yeo, G Tukeman… - Aids, 2019 - journals.lww.com
Objective: Maternal folate (vitamin B9) status is the largest known modifier of neural tube
defect risk, so we evaluated folate-related mechanisms of action for dolutegravir (DTG) …

[HTML][HTML] ROS chronicles in HIV infection: genesis of oxidative stress, associated pathologies, and therapeutic strategies

R Harshithkumar, P Shah, P Jadaun… - Current issues in …, 2024 - mdpi.com
Reactive oxygen species (ROS) are widely regarded as signaling molecules and play
essential roles in various cellular processes, but when present in excess, they can lead to …

Eryptosis-the neglected cause of anemia in end stage renal disease

F Lang, R Bissinger, M Abed, F Artunc - Kidney and Blood Pressure …, 2017 - karger.com
End stage renal disease (ESRD) invariably leads to anemia which has been mainly
attributed to compromised release of erythropoietin from the defective kidneys with …

Dolutegravir derivative inhibits proliferation and induces apoptosis of non-small cell lung cancer cells via calcium signaling pathway

WJ Wang, LF Mao, HL Lai, YW Wang, ZB Jiang… - Pharmacological …, 2020 - Elsevier
Non-small cell lung cancer (NSCLC) is the most prevalent type of lung cancer. However,
there has been little improvement in its cure rate in the last 30 years, due to its intricate …

[HTML][HTML] Methods employed in cytofluorometric assessment of eryptosis, the suicidal erythrocyte death

M Jemaà, M Fezai, R Bissinger, F Lang - Cellular Physiology and …, 2017 - karger.com
Suicidal erythrocyte death or eryptosis contributes to or even accounts for anemia in a wide
variety of clinical conditions, such as iron deficiency, dehydration, hyperphosphatemia …