[HTML][HTML] Glutamate excitotoxicity: Potential therapeutic target for ischemic stroke
Z Shen, M Xiang, C Chen, F Ding, Y Wang… - Biomedicine & …, 2022 - Elsevier
Glutamate-mediated excitotoxicity is an important mechanism leading to post ischemic
stroke damage. After acute stroke, the sudden reduction in cerebral blood flow is most …
stroke damage. After acute stroke, the sudden reduction in cerebral blood flow is most …
Pharmacogenetics and pharmacotherapy of military personnel suffering from post-traumatic stress disorder
T Efferth - Current neuropharmacology, 2017 - ingentaconnect.com
Background: Posttraumatic stress disorder (PTSD) is a severe problem among soldiers with
combating experience difficult to treat. The pathogenesis is still not fully understood at the …
combating experience difficult to treat. The pathogenesis is still not fully understood at the …
Identification of a new class of selective excitatory amino acid transporter subtype 1 (EAAT1) inhibitors followed by a structure–activity relationship study
SW Hansen, MN Erichsen, B Fu… - Journal of Medicinal …, 2016 - ACS Publications
Screening of a small compound library at the three excitatory amino acid transporter
subtypes 1–3 (EAAT1–3) resulted in the identification of compound (Z)-4-chloro-3-(5-((3-(2 …
subtypes 1–3 (EAAT1–3) resulted in the identification of compound (Z)-4-chloro-3-(5-((3-(2 …
Bioavailability Studies and in vitro Profiling of the Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitor UCPH‐102
I Haym, THV Huynh, SW Hansen… - …, 2016 - Wiley Online Library
Although the selective excitatory amino acid transporter subtype 1 (EAAT1) inhibitor UCPH‐
101 has become a standard pharmacological tool compound for in vitro and ex vivo studies …
101 has become a standard pharmacological tool compound for in vitro and ex vivo studies …
New Insight into the Structure–Activity Relationships of the Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitors UCPH‐101 and UCPH‐102
SW Hansen, MN Erichsen, THV Huynh… - …, 2016 - Wiley Online Library
In the present study, we made further investigations on the structure–activity requirements of
the selective excitatory amino acid transporter 1 (EAAT1) inhibitor, 2‐amino‐4‐(4 …
the selective excitatory amino acid transporter 1 (EAAT1) inhibitor, 2‐amino‐4‐(4 …
[图书][B] Role of nuclear metabotropic glutamate receptor 5 in rat models of persistent pain
K Vincent - 2017 - search.proquest.com
Abstract Metabotropic glutamate receptor 5 (mGluR5) is an excitatory G protein-coupled
receptor present in the spinal cord dorsal horn (SCDH), where it has a well-established role …
receptor present in the spinal cord dorsal horn (SCDH), where it has a well-established role …