Microcins in Enterobacteriaceae: Peptide Antimicrobials in the Eco-Active Intestinal Chemosphere

F Baquero, VF Lanza, MR Baquero… - Frontiers in …, 2019 - frontiersin.org
Microcins are low-molecular-weight, ribosomally produced, highly stable, bacterial-inhibitory
molecules involved in competitive, and amensalistic interactions between …

Bacteriocins to thwart bacterial resistance in gram negative bacteria

S Telhig, L Ben Said, S Zirah, I Fliss… - Frontiers in …, 2020 - frontiersin.org
An overuse of antibiotics both in human and animal health and as growth promoters in
farming practices has increased the prevalence of antibiotic resistance in bacteria. Antibiotic …

What approaches to thwart bacterial efflux pumps-mediated resistance?

AJ Seukep, HG Mbuntcha, V Kuete, Y Chu, E Fan… - Antibiotics, 2022 - mdpi.com
An effective response that combines prevention and treatment is still the most anticipated
solution to the increasing incidence of antimicrobial resistance (AMR). As the phenomenon …

Mitochondrial Volume Regulation and Swelling Mechanisms in Cardiomyocytes

XR Chapa-Dubocq, KM Rodríguez-Graciani… - Antioxidants, 2023 - mdpi.com
Mitochondrion, known as the “powerhouse” of the cell, regulates ion homeostasis, redox
state, cell proliferation and differentiation, and lipid synthesis. The inner mitochondrial …

Antibacterial action, proteolytic immunity, and in vivo activity of a Vibrio cholerae microcin

SY Kim, JR Randall, R Gu, QD Nguyen, BW Davies - Cell Host & Microbe, 2024 - cell.com
Microcins are small antibacterial proteins that mediate interbacterial competition. Their
narrow-spectrum activity provides opportunities to discover microbiome-sparing treatments …

Mini-Review: Antibiotic-Resistant Escherichia coli from Farm Animal-Associated Sources

C Xu, L Kong, Y Liao, Y Tian, Q Wu, H Liu, X Wang - Antibiotics, 2022 - mdpi.com
Escherichia coli is one of the most frequent causes of gastro-intestinal and extra-intestinal
diseases in animals and humans. Due to overuse and misuse of antibiotics, recent years …

Resistance Mechanism and Physiological Effects of Microcin Y in Salmonella enterica subsp. enterica Serovar Typhimurium

Y Han, Y Li, Z Zeng, W Li, S Feng… - Microbiology Spectrum, 2022 - Am Soc Microbiol
Salmonella bacteria pose a significant threat to animal husbandry and human health due to
their virulence and multidrug resistance. The lasso peptide MccY is a recently discovered …

Non-antibiotic antibacterial peptides and proteins of Escherichia coli: efficacy and potency of bacteriocins

J Bosák, M Hrala, L Micenková… - Expert Review of Anti …, 2021 - Taylor & Francis
Introduction The emergence and spread of antibiotic resistance among pathogenic bacteria
drives the search for alternative antimicrobial therapies. Bacteriocins represent a potential …

The “cins” of our fathers: Rejuvenated interest in colicins to combat drug resistance

S Upatissa, RJ Mitchell - Journal of Microbiology, 2023 - Springer
With the growing threat of antibiotic resistance, researchers around the globe are seeking
alternatives to stem bacterial pathogenesis. One such alternative is bacteriocins, proteins …

Class IIb Microcin MccM Interferes with Oxidative Phosphorylation in Escherichia coli

KKA Wang, J Singh, JS Albin, BL Pentelute… - ACS Chemical …, 2024 - ACS Publications
Dysbiosis of the human gut microbiota is linked to numerous diseases. Understanding the
molecular mechanisms by which microbes interact and compete with one another is …