Acute liver failure (ALF) is a rare but challenging clinical syndrome with multiple causes; a
specific etiology cannot be identified in 15% of adult and 50% of pediatric cases. The course …

Autoimmune hepatitis is characterized by autoantibodies, hypergammaglobulinemia, and
interface hepatitis on histological examination. The features lack diagnostic specificity, and …

Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALF, acute liver failure; ALT, alanine aminotransferase; AMA …

Each Association appointed at least one author to serve on the writing group. The Chair of
the writing group was appointed by the AASLD. Members of the writing group were not …

Autoimmune hepatitis is associated with varied clinical presentations and natural history, as
well as somewhat unpredictable treatment responses. Understanding how to stratify patients …

Acute liver failure (ALF) in children differs from that observed in adults in both the etiologic
spectrum and the clinical picture. Children, particularly very young ones, do not demonstrate …

Drug-induced acute liver failure (ALF) accounts for approximately 20% of ALF in children
and a higher percentage of ALF in adults. Although most patients experience milder drug …

Autoimmune hepatitis frequently has an abrupt onset of symptoms, and it can present with
acute liver failure. The abrupt presentation can indicate spontaneous exacerbation of a pre …

Liver transplantation (LT) is the only proven treatment for pediatric acute liver failure (PALF).
However, over a period of time, spontaneous native liver survival is increasingly reported …

Objectives: Hepatic encephalopathy (HE) is challenging to identify in children with acute
liver failure and was not a requirement for enrollment into the Pediatric Acute Liver Failure …