Extraintestinal Pathogenic Escherichia coli: Virulence Factors and Antibiotic Resistance
The One Health approach emphasizes the importance of antimicrobial resistance (AMR) as
a major concern both in public health and in food animal production systems. As a general …
a major concern both in public health and in food animal production systems. As a general …
[HTML][HTML] The type 1 secretion pathway—the hemolysin system and beyond
S Thomas, IB Holland, L Schmitt - … et Biophysica Acta (BBA)-Molecular Cell …, 2014 - Elsevier
Type 1 secretion systems (T1SS) are wide-spread among Gram-negative bacteria. An
important example is the secretion of the hemolytic toxin HlyA from uropathogenic strains …
important example is the secretion of the hemolytic toxin HlyA from uropathogenic strains …
Genetic diseases of PIEZO1 and PIEZO2 dysfunction
SL Alper - Current topics in membranes, 2017 - Elsevier
Mutations in the genes encoding the mechanosensitive cation channels PIEZO1 and
PIEZO2 are responsible for multiple hereditary human diseases. Loss-of-function mutations …
PIEZO2 are responsible for multiple hereditary human diseases. Loss-of-function mutations …
[HTML][HTML] Hemolysin of uropathogenic Escherichia coli: A cloak or a dagger?
LC Ristow, RA Welch - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2016 - Elsevier
Hemolysin from uropathogenic Escherichia coli (UPEC) is a hemolytic and cytotoxic protein
active against a broad range of species and cell types. Expression of hemolysin correlates …
active against a broad range of species and cell types. Expression of hemolysin correlates …
Calmodulin‐dependent activation of the epithelial calcium‐dependent chloride channel TMEM16A
Y Tian, P Kongsuphol, M Hug… - The FASEB …, 2011 - Wiley Online Library
TMEM16A (anoctamin 1, Ano1), a member of a family of 10 homologous proteins, has been
shown to form an essential component of Ca2+‐activated CU channels. TMEM16A‐null …
shown to form an essential component of Ca2+‐activated CU channels. TMEM16A‐null …
Microparticles: a critical component in the nexus between inflammation, immunity, and thrombosis
O Morel, N Morel, L Jesel, JM Freyssinet… - Seminars in …, 2011 - Springer
Plasma membrane remodeling characterized by phosphatidylserine exposure and
consecutive microparticle (MP) shedding is an ubiquitous process enabling the clearance of …
consecutive microparticle (MP) shedding is an ubiquitous process enabling the clearance of …
Erythrocyte-mediated delivery of bioorthogonal nanozymes for selective targeting of bacterial infections
Bioorthogonal transformation of imaging and therapeutic substrates using transition metal
catalysts (TMCs) provides a toolkit with diverse applications in biomedicine. Controlled …
catalysts (TMCs) provides a toolkit with diverse applications in biomedicine. Controlled …
Anoctamins
K Kunzelmann, Y Tian, JR Martins, D Faria… - … -European Journal of …, 2011 - Springer
Abstract Endogenous Ca 2+-activated Cl− channels (CaCC) demonstrate biophysical and
pharmacological properties that are well represented in cells overexpressing anoctamin 1 …
pharmacological properties that are well represented in cells overexpressing anoctamin 1 …
Shiga toxin–induced complement-mediated hemolysis and release of complement-coated red blood cell–derived microvesicles in hemolytic uremic syndrome
I Arvidsson, A Ståhl, M Manea Hedström… - The Journal of …, 2015 - journals.aai.org
Abstract Shiga toxin (Stx)-producing Escherichia coli (STEC) cause hemolytic uremic
syndrome (HUS). This study investigated whether Stx2 induces hemolysis and whether …
syndrome (HUS). This study investigated whether Stx2 induces hemolysis and whether …
The chloride anion as a signalling effector
ÁG Valdivieso, TA Santa‐Coloma - Biological Reviews, 2019 - Wiley Online Library
The specific role of the chloride anion (Cl−) as a signalling effector or second messenger
has been increasingly recognized in recent years. It could represent a key factor in the …
has been increasingly recognized in recent years. It could represent a key factor in the …