Schizophrenia is frequently a chronic and disabling disorder, characterized by
heterogeneous positive and negative symptom constellations. The objective of this review …

Negative symptoms of schizophrenia are associated with poor functional outcome and place
a substantial burden on people with this disorder, their families, and health-care systems …

Objective: Research in both animals and humans indicates that cannabidiol (CBD) has
antipsychotic properties. The authors assessed the safety and effectiveness of CBD in …

Antipsychotic drugs are central to the treatment of schizophrenia and other psychotic
disorders but are ineffective for some patients and associated with side-effects and …

Schizophrenia is a chronic and severe psychiatric disorder that has profound impact on an
individual's life and on society. Thus, developing more effective therapeutic interventions is …

Outcomes of psychotic disorders are associated with high personal, familiar, societal and
clinical burden. There is thus an urgent clinical and societal need for improving those …

The Hierarchical Taxonomy of Psychopathology (HiTOP) is a scientific effort to address
shortcomings of traditional mental disorder diagnoses, which suffer from arbitrary …

Objective: Antipsychotic drug efficacy may have decreased over recent decades. The
authors present a meta-analysis of all placebo-controlled trials in patients with acute …

Psychosocial interventions are recommended in schizophrenia and first-episode
psychosis/early psychosis (EP). Nevertheless, literature is heterogeneous and often …

Introduction Childhood trauma is a risk factor for the development of psychosis. Furthermore,
a number of theories propose specific mechanisms by which childhood trauma may …