Over the last decade, single-cell genomics has revealed remarkable heterogeneity and
plasticity of cell types in the lungs and airways. The challenge now is to understand how …

Lung cancer is a deadly disease with the highest rates of mortality. Over recent decades, a
better understanding of the biological mechanisms implicated in its pathogenesis has led to …

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease characterized by repetitive
alveolar injuries with excessive deposition of extracellular matrix (ECM) proteins. A crucial …

Objective: With the acceleration of industrialization, air pollution has become a global
environmental issue, particularly in cold regions where the unique climatic and geographical …

Background Pulmonary arterial hypertension (PAH) is a severe lung condition with unmet
clinical needs, marked by endothelial damage, excessive repair, and arterial narrowing …

In an era where transcriptomics-based subtyping, phenotyping and mechanistic
understanding is increasingly being driven by state-of-the-art spatially resolved …