Immunological mechanisms of allergen-specific immunotherapy
Allergen-specific immunotherapy has been carried out for almost a century and remains one
of the few antigen-specific treatments for inflammatory diseases. The mechanisms by which …
of the few antigen-specific treatments for inflammatory diseases. The mechanisms by which …
Role of Treg in immune regulation of allergic diseases
Allergy is a Th2‐mediated disease that involves the formation of specific IgE antibodies
against innocuous environmental substances. The prevalence of allergic diseases has …
against innocuous environmental substances. The prevalence of allergic diseases has …
Sub-Lingual Immunotherapy: World Allergy Organization Position Paper 2009
GW Canonica, J Bousquet, T Casale… - World Allergy …, 2009 - Springer
Sublingual immunotherapy (SLIT) has gained wide accep-tance in many European
countries and has raised the level of interest in immunotherapy among practicing allergists …
countries and has raised the level of interest in immunotherapy among practicing allergists …
Long-term clinical efficacy in grass pollen–induced rhinoconjunctivitis after treatment with SQ-standardized grass allergy immunotherapy tablet
BACKGROUND: Sustained and disease-modifying effects of sublingual immunotherapy
have never before been confirmed in a large-scale randomized, double-blind, placebo …
have never before been confirmed in a large-scale randomized, double-blind, placebo …
Mechanisms of allergen-specific immunotherapy
Allergen-specific immunotherapy (SIT) has been used for almost a century as a
desensitizing therapy for allergic diseases and represents the only curative and specific …
desensitizing therapy for allergic diseases and represents the only curative and specific …
Mechanisms and treatment of allergic disease in the big picture of regulatory T cells
Various populations of regulatory T (Treg) cells have been shown to play a central role in the
maintenance of peripheral homeostasis and the establishment of controlled immune …
maintenance of peripheral homeostasis and the establishment of controlled immune …
Safety and efficacy in children of an SQ-standardized grass allergen tablet for sublingual immunotherapy
A Bufe, P Eberle, E Franke-Beckmann, J Funck… - Journal of Allergy and …, 2009 - Elsevier
BACKGROUND: Immunotherapy with the standardized quality grass tablet Grazax is
efficacious and well-tolerated in adult patients with rhinoconjunctivitis. Allergic asthma and …
efficacious and well-tolerated in adult patients with rhinoconjunctivitis. Allergic asthma and …
Sublingual grass pollen immunotherapy is associated with increases in sublingual Foxp3‐expressing cells and elevated allergen‐specific immunoglobulin G4 …
GW Scadding, MH Shamji… - Clinical & …, 2010 - Wiley Online Library
Background The mechanisms of sublingual immunotherapy (SLIT) are less well understood
than those of subcutaneous immunotherapy (SCIT). Objectives To determine the effects of …
than those of subcutaneous immunotherapy (SCIT). Objectives To determine the effects of …
New insights in mucosal vaccine development
V Pavot, N Rochereau, C Genin, B Verrier, S Paul - Vaccine, 2012 - Elsevier
Mucosal surfaces are the major entrance for infectious pathogens and therefore mucosal
immune responses serve as a first line of defence. Most current immunization procedures …
immune responses serve as a first line of defence. Most current immunization procedures …
Therapeutic manipulation of immune tolerance in allergic disease
Immune tolerance—the adaptation of the immune system to external antigens or allergens—
might be therapeutically manipulated to restore normal immunity in conditions such as …
might be therapeutically manipulated to restore normal immunity in conditions such as …