Metformin as a first-line drug for type 2 diabetes mellitus (T2DM) treatment is widely studied.
Metformin can reduce liver glucose output and improve insulin resistance. Recent evidence …

Cerebral ischaemia/reperfusion (I/R) injury is the transient loss, followed by rapid return, of
blood flow to the brain. This condition is often caused by strokes and heart attacks. The …

We asked whether pharmacological stimulation of endogenous neural precursor cells
(NPCs) may promote cognitive recovery and brain repair, focusing on the drug metformin, in …

3300 Stroke November 2019 allow more realistic and precise testing of cell delivery
techniques including stereotaxic and intra-arterial cell administration and dose translation to …

Ischemic stroke occurs when the arteries supplying blood to the brain are narrowed or
blocked, inducing damage to brain tissue due to a lack of blood supply. One effective way to …

Periodontal ligament stem cell (PDLSC)-based tissue engineering is an important method
for regenerating lost bone in periodontitis. Maintaining or enhancing the osteogenic …

Metformin is a first-line medication for type II diabetes. Numerous studies have shown that
metformin not only has hypoglycemic effects, but also modulates many physiological and …

Stem cells have been used for regenerative and therapeutic purposes in a variety of
diseases. In ischemic brain injury, preclinical studies have been promising, but have failed …

The strong evidence of metformin use in subjects affected by type 2 diabetes (T2DM) on
health outcomes, together with data from pre-clinical studies, has led the gerontological …

Stem cell transplantation with rehabilitation therapy presents an effective stroke treatment.
Here, we discuss current breakthroughs in stem cell research along with rehabilitation …