Chemotherapy is a well-known and effective treatment for different cancers; unfortunately, it
has not been as efficient in the eradication of all cancer cells as been expected. The …

The tumor microenvironment (TME) is an intricate system within solid neoplasms. In this
review, we aim to provide an updated insight into the TME with a focus on the effects of …

New opportunities are needed to increase immune checkpoint blockade (ICB) benefit.
Whereas the interferon (IFN) γ pathway harbors both ICB resistance factors and therapeutic …

Nutrigenomics data on the functional components of olive oil are still sparse, but rapidly
increasing. Olive oil is the main source of fat and health‐promoting component of the …

Tumor necrosis factor (TNF), initially reported to induce tumor cell apoptosis and cachexia, is
now considered a central mediator of a broad range of biological activities from cell …

Cancer is one of the leading causes of morbidity and mortality worldwide. Traditional
treatments include surgery, chemotherapy and radiation therapy, and more recently targeted …

Abstract Tumor-associated macrophage (TAM)-related immunotherapy is a greatly
promising strategy that involves altering the immunosuppressive tumor microenvironment …

Tumor necrosis factor (TNF) is widely accepted as a tumor-suppressive cytokine via its
ubiquitous receptor TNF receptor 1 (TNFR1). The other receptor, TNFR2, is not only …

Simple Summary Breast cancer is one of the main causes of morbidity and mortality in
women. Early breast cancer has a relatively good prognosis, in contrast to metastatic …

Metastasis is a multi-step process that ultimately depends on the ability of disseminating
cancer cells to establish favorable communications with their microenvironment. The tumor …