The pathophysiologic mechanisms underlying diabetic polyneuropathy are complex.
Several pathways are thought to contribute to the development of diabetic neuropathy …

Objective Research has revealed that patients with diabetes and peripheral neuropathy
exhibit significantly elevated nerve stimulation thresholds. However, the minimum …

Animal data have demonstrated increased block duration after local anaesthetic injections in
diabetic rat models. Whether the same is true in humans is currently undefined. We …

Background Neurotoxicity induced by local anesthetics (LAs) is potentially life threatening,
especially for patients with underlying diseases like diabetes. The anesthetic bupivacaine …

Little is known regarding the pharmacological properties of extended-release local
anesthetics in the setting of diabetic peripheral neuropathy. We investigated and compared …

Background and objectives The effect of intravenous dexamethasone on the duration of
axillary plexus block performed using ropivacaine is not described. The aim of this study is to …

Purpose This clinical trial aimed to evaluate and compare parameters of intraoral soft tissue
anesthesia and cardiovascular function, and prevalence of local side effects in patients with …

Purpose Ultrasound-guided supraclavicular brachial plexus block (SCBPB) is performed by
surgeons for upper limb anesthesia; however, certain patients need additional local …

Nerves in patients with diabetic neuropathy (DN) show increased susceptibility to local
anesthetics, potentially requiring a decreased dose. We investigated whether the minimum …

Objective: Diabetic neuropathy is one of the most common complications of diabetes
mellitus. Recovery from peripheral nerve blocks in diabetic patients with neuropathy may be …