Solving stochastic gene expression models using queueing theory: a tutorial review

J Szavits-Nossan, R Grima - arXiv preprint arXiv:2307.03253, 2023 - arxiv.org
Stochastic models of gene expression are typically formulated using the chemical master
equation, which can be solved exactly or approximately using a repertoire of analytical …

Bye bye, linearity, bye: quantification of the mean for linear CRNs in a random environment

M Sinzger-D'Angelo, S Startceva, H Koeppl - Journal of Mathematical …, 2023 - Springer
Molecular reactions within a cell are inherently stochastic, and cells often differ in
morphological properties or interact with a heterogeneous environment. Consequently, cell …

Solving stochastic gene expression models using queueing theory: a tutorial review

J Szavits-Nossan, R Grima - Biophysical Journal, 2024 - cell.com
Stochastic models of gene expression are typically formulated using the chemical master
equation, which can be solved exactly or approximately using a repertoire of analytical …

A functional central limit theorem for a Markov-modulated infinite-server queue

D Anderson, J Blom, M Mandjes, H Thorsdottir… - … and Computing in …, 2016 - Springer
We consider a model in which the production of new molecules in a chemical reaction
network occurs in a seemingly stochastic fashion, and can be modeled as a Poisson …

Infinite-server queueing tandem with Markovian arrival process and service depending on its state

A Moiseev, M Shklennik, E Polin - Annals of Operations Research, 2023 - Springer
We consider the infinite-server queueing tandem with the Markovian arrival process. The
service time of requests at the first stage and the probability of their transition to the second …

Pseudo steady-state period in non-stationary infinite-server queue with state dependent arrival intensity

A Nazarov, A Dudin, A Moiseev - Mathematics, 2022 - mdpi.com
An infinite-server queueing model with state-dependent arrival process and exponential
distribution of service time is analyzed. It is assumed that the difference between the value of …

Markov-modulated ornstein–uhlenbeck processes

G Huang, HM Jansen, M Mandjes, P Spreij… - Advances in Applied …, 2016 - cambridge.org
In this paper we consider an Ornstein–Uhlenbeck (OU) process (M (t)) t≥ 0 whose
parameters are determined by an external Markov process (X (t)) t≥ 0 on a finite state space …

[HTML][HTML] The M/M/C queueing system in a random environment

Z Liu, S Yu - Journal of Mathematical Analysis and Applications, 2016 - Elsevier
Abstract An M/M/C queueing system operating in a Markovian environment is studied. This
paper focuses on the stationary behavior and presents the theoretical framework. For a …

A multi-server queue in a multi-phase random environment with waiting servers and customers' impatience under synchronous working vacation policy

M Houalef, AA Bouchentouf, L Yahiaoui - Journal of the Operations …, 2023 - Springer
In this paper, we develop an M/M/c queueing system in a Markovian environment with
waiting servers, balking and reneging, under both synchronous single and multiple working …

Functional central limit theorems for Markov-modulated infinite-server systems

J Blom, K De Turck, M Mandjes - Mathematical Methods of Operations …, 2016 - Springer
In this paper we study the Markov-modulated M/M/∞∞ queue, with a focus on the
correlation structure of the number of jobs in the system. The main results describe the …