Therapeutic antibodies in medicine

P Sharma, RV Joshi, R Pritchard, K Xu, MA Eicher - Molecules, 2023 - mdpi.com
Antibody engineering has developed into a wide-reaching field, impacting a multitude of
industries, most notably healthcare and diagnostics. The seminal work on developing the …

Development, methodological evaluation and application of a cell-based TRF assay for analysis of ADCC activity

X Zhu, L Gong, Q Qin - Journal of Pharmaceutical and Biomedical Analysis, 2023 - Elsevier
Interaction of an antibody with its FcγR plays an important role in effector functions such as
antibody-dependent cell-mediated cytotoxicity (ADCC). Nowadays altered ADCC activity of …

Treatment patterns and factors associated with discontinuation of monoclonal antibodies

MMS Alkaabi, SA Rabbani, PGM Rao… - SAGE Open …, 2024 - journals.sagepub.com
Background: Biological agents have revolutionized care in specialties such as oncology,
immunology, infectious diseases, and genetic disorders, offering targeted actions on specific …

[HTML][HTML] Bioconjugation of antibodies and affinity proteins for the development of novel diagnostic and therapeutic tools

A Nagy - 2024 - diva-portal.org
Antibodies and affinity proteins are essential tools in research, diagnostics and therapy.
Antibodies have the ability to bind to a large variety of protein targets with great specificity …

Immune-mediated complications of monoclonal antibodies used in onco-hematology.

I Iordan, DC Jinga, CD Popescu… - Oncolog …, 2023 - search.ebscohost.com
Monoclonal antibodies have emerged as effective treat ments for a wide range of
hematological and oncological dis or ders. Even though the majority of these medications …