Aims Sick sinus syndrome (SSS) and atrial fibrillation (AF) frequently coexist and show a
bidirectional relationship. This systematic review and meta-analysis aimed to decipher the …

As a common cardiovascular disease (CVD), Arrhythmia refers to any abnormality in the
origin, frequency, rhythm, conduction velocity, timing, pathway, sequence, or other aspect of …

Background Mice with deletion of complex I subunit Ndufs4 develop mitochondrial
encephalomyopathy resembling Leigh syndrome (LS). The metabolic derangement and …

Sinoatrial node fibrosis is involved in the pathogenesis of sinus sick syndrome (SSS).
Transient receptor potential (TRP) subfamily M member 7 (TRPM7) is implicated in cardiac …

Background. The transient outward potassium current (Ito) and the ultrarapid delayed
rectifier potassium current (IKur) are major potassium currents involved in the repolarization …

Background: Catheter ablation of atrial fibrillation is an alternative treatment for patients with
tachycardia-bradycardia syndrome (TBS) to avoid pacemaker implantation. The risk …

Atrial fibrillation (AF) is currently defined as symptomatic by asking patients if they are aware
of when they are in AF and if they feel better in sinus rhythm. However, this approach of …

Cardiac side effects of some pulmonary drugs are observed in clinical practice.
Aminophylline, a methylxanthine bronchodilator with documented proarrhythmic action, may …

Sudden alterations in the heart rate may be associated with diverse symptoms. Sinus node
dysfunction (SND), also known as sick sinus syndrome, is a sinoatrial (SA) node disorder …

Background. Atrial fibrillation (AF) is the most common heart rhythm disorder that has been
shown to be associated with a significant increase in stroke and systemic embolism risk. The …