Despite recent therapeutic advances in cancer treatment, metastasis remains the principal
cause of cancer death. Recent work has uncovered the unique biology of metastasis …

MicroRNAs (miRNAs) are a group of small non-coding RNAs that post-transcriptionally
control expression of genes by targeting mRNAs. miRNA alterations partake in the …

microRNAs (miRNAs) are small non-coding RNA molecules, evolutionary conserved. They
target more than one mRNAs, thus influencing multiple molecular pathways, but also …

Metastasis is the main cause of death in people with cancer. To colonize distant organs,
circulating tumour cells must overcome many obstacles through mechanisms that we are …

Tumour metastasis, the movement of tumour cells from a primary site to progressively
colonize distant organs, is a major contributor to the deaths of cancer patients. Therapeutic …

N6‐Methyladenosine (m6A) modification has been implicated in many biological processes.
However, its role in cancer has not been well studied. Here, we demonstrate that m6A …

Summary N 6-methyladenosine (m 6 A) is the most abundant internal modification of
messenger RNA. While the presence of m 6 A on transcripts can impact nuclear RNA fates …

Following a diagnosis of breast cancer, the most immediate challenges in patient
management are the determination of prognosis and identification of the most appropriate …

The first step in the biogenesis of microRNAs is the processing of primary microRNAs (pri-
miRNAs) by the microprocessor complex, composed of the RNA-binding protein DGCR8 …

Upon exposure to stress, tRNAs are enzymatically cleaved, yielding distinct classes of tRNA-
derived fragments (tRFs). We identify a novel class of tRFs derived from tRNA Glu, tRNA …