Clinical features, diagnosis, and management of enterovirus 71

MH Ooi, SC Wong, P Lewthwaite, MJ Cardosa… - The Lancet …, 2010 - thelancet.com
Although poliomyelitis has been mostly eradicated worldwide, large outbreaks of the related
enterovirus 71 have been seen in Asia-Pacific countries in the past 10 years. This virus …

Human enterovirus 71 and hand, foot and mouth disease

SSY Wong, CCY Yip, SKP Lau, KY Yuen - Epidemiology & Infection, 2010 - cambridge.org
Hand, foot and mouth disease (HFMD) is generally a benign febrile exanthematous
childhood disease caused by human enteroviruses. The route of transmission is postulated …

Antiviral efficacy of flavonoids against enterovirus 71 infection in vitro and in newborn mice

W Dai, J Bi, F Li, S Wang, X Huang, X Meng, B Sun… - Viruses, 2019 - mdpi.com
Enterovirus 71 (EV71) infection is known to cause hand, foot, and mouth disease (HFMD),
which is associated with neurological complications; however, there is currently no effective …

Identification and validation of clinical predictors for the risk of neurological involvement in children with hand, foot, and mouth disease in Sarawak

MH Ooi, SC Wong, A Mohan, Y Podin, D Perera… - BMC Infectious …, 2009 - Springer
Abstract Background Human enterovirus 71 (HEV71) can cause Hand, foot, and mouth
disease (HFMD) with neurological complications, which may rapidly progress to fulminant …

Management of viral central nervous system infections: a primer for clinicians

PB Bookstaver, PL Mohorn, A Shah… - Journal of central …, 2017 - journals.sagepub.com
Viruses are a common cause of central nervous system (CNS) infections with many host,
agent, and environmental factors influencing the expression of viral diseases. Viruses can …

Understanding enterovirus 71 neuropathogenesis and its impact on other neurotropic enteroviruses

KC Ong, KT Wong - Brain pathology, 2015 - Wiley Online Library
Abstract E nterovirus A71 (EV‐A71) belongs to the species group A in the E nterovirus
genus within the P icornaviridae family. EV‐A71 usually causes self‐limiting hand, foot and …

Epidemiological and etiological characteristics of hand, foot, and mouth disease in Wuhan, China from 2012 to 2013: outbreaks of coxsackieviruses A10

Q Yang, J Ding, J Cao, Q Huang… - Journal of medical …, 2015 - Wiley Online Library
Hand‐foot‐mouth disease (HFMD) is a common infectious disease which often occurs in
young children. It is caused by enteroviruses, most commonly enterovirus71 (EV71) and …

Developments towards antiviral therapies against enterovirus 71

KX Wu, MML Ng, JJH Chu - Drug discovery today, 2010 - Elsevier
Enterovirus 71 (EV71) has emerged as a clinically important neurotropic virus that can
cause acute flaccid paralysis and encephalitis, leading to cardiopulmonary failure and …

Enteroviral encephalitis in children: clinical features, pathophysiology, and treatment advances

S Jain, B Patel, GC Bhatt - Pathogens and global health, 2014 - Taylor & Francis
Enteroviruses (EVs) have emerged as one of the important etiological agents as a causative
organism for encephalitis, especially in children and adults. After the first report of EV …

The risk factors of acquiring severe hand, foot, and mouth disease: a meta‐analysis

BJ Sun, HJ Chen, Y Chen, XD An… - Canadian Journal of …, 2018 - Wiley Online Library
Objectives. The incidence of severe hand, foot, and mouth disease (HFMD) is not low,
especially in mainland China in almost every year recently. In this study, we conducted a …