Compulsivity in obsessive–compulsive disorder and addictions

M Figee, T Pattij, I Willuhn, J Luigjes… - European …, 2016 - Elsevier
Compulsive behaviors are driven by repetitive urges and typically involve the experience of
limited voluntary control over these urges, a diminished ability to delay or inhibit these …

Animal models to improve our understanding and treatment of suicidal behavior

TD Gould, P Georgiou, LA Brenner, L Brundin… - Translational …, 2017 - nature.com
Worldwide, suicide is a leading cause of death. Although a sizable proportion of deaths by
suicide may be preventable, it is well documented that despite major governmental and …

How distinct functional insular subdivisions mediate interacting neurocognitive systems

H Zhao, O Turel, A Bechara, Q He - Cerebral Cortex, 2023 - academic.oup.com
Recent neurocognitive models propose that the insula serves as a hub of interoceptive
awareness system, modulating 2 interplaying neurocognitive systems: The posterior insula …

Neural predictors and mechanisms of cognitive behavioral therapy on threat processing in social anxiety disorder

H Klumpp, DA Fitzgerald, KL Phan - Progress in Neuro …, 2013 - Elsevier
Cognitive behavioral therapy (CBT) is “gold standard” psychotherapy for social anxiety
disorder (SAD). Cognitive models posit that preferential processing of threat mediates …

Self-awareness in neurodegenerative disease relies on neural structures mediating reward-driven attention

T Shany-Ur, N Lin, HJ Rosen, M Sollberger, BL Miller… - Brain, 2014 - academic.oup.com
Accurate self-awareness is essential for adapting one's tasks and goals to one's actual
abilities. Patients with neurodegenerative diseases, particularly those with right frontal …

Uncertainty during pain anticipation: the adaptive value of preparatory processes

EM Seidel, DM Pfabigan, A Hahn, R Sladky… - Human Brain …, 2015 - Wiley Online Library
Objectives: Anticipatory processes prepare the organism for upcoming experiences. The aim
of this study was to investigate neural responses related to anticipation and processing of …

Effects of reduced weight maintenance and leptin repletion on functional connectivity of the hypothalamus in obese humans

W Hinkle, M Cordell, R Leibel, M Rosenbaum, J Hirsch - PloS one, 2013 - journals.plos.org
Treating obesity has proven to be an intractable challenge, in part, due to the difficulty of
maintaining reduced weight. In our previous studies of in-patient obese subjects, we have …

Resting state functional connectivity of the basal nucleus of Meynert in humans: in comparison to the ventral striatum and the effects of age

RL Chiang-shan, JS Ide, S Zhang, S Hu, HH Chao… - Neuroimage, 2014 - Elsevier
The basal nucleus of Meynert (BNM) provides the primary cholinergic inputs to the cerebral
cortex. Loss of neurons in the BNM is linked to cognitive deficits in Alzheimer's disease and …

Neural representation of valenced and generic probability and uncertainty

JC Kim, L Hellrung, M Grueschow, S Nebe… - Journal of …, 2024 - jneurosci.org
Representing the probability and uncertainty of outcomes facilitates adaptive behavior by
allowing organisms to prepare in advance and devote attention to relevant events …

Is brain response to food rewards related to overeating? A test of the reward surfeit model of overeating in children

S Adise, CF Geier, NJ Roberts, CN White, KL Keller - Appetite, 2018 - Elsevier
The reward surfeit model of overeating suggests that heightened brain response to rewards
contributes to overeating and subsequent weight gain. However, previous studies have not …