Effective regeneration of bone defects often presents significant challenges, particularly in
patients with decreased tissue regeneration capacity due to extensive trauma, disease …

The biological interface between an orthopedic implant and the surrounding host tissue may
have a dramatic effect upon clinical outcome. Desired effects include bony ingrowth …

Bone tissue engineering approaches have evolved towards addressing the challenges of
tissue mimetic requirements over the years. Different strategies have been combining …

Cellular strategies play an important role in bone tissue engineering and regenerative
medicine (BTE/RM). Variability in cell culture procedures (eg, cell types, cell isolation and …

With the in-depth understanding of bone regeneration mechanisms and the development of
bone tissue engineering, a variety of scaffold carrier materials with desirable …

Autologous bone grafting (ABG) remains entrenched as the gold standard of treatment in
bone regenerative surgery. Consequently, many marginally successful bone tissue …

The effective osteogenic commitment of human bone marrow mesenchymal stem cells
(hBMSCs) is critical for bone regenerative therapies. Extracellular vesicles (EVs) derived …

The availability of engineered biological tissues holds great potential for both clinical
applications and basic research in a life science laboratory. A prototype standalone …

Tissue Engineering (TE) is a scientific field mainly focused on the development of tissue and
organ substitutes by controlling biological, biophysical and/or biomechanical parameters in …

Background Due to unmet need for bone augmentation, our aim was to promote osteogenic
differentiation of human adipose stem cells (hASCs) encapsulated in gellan gum (GG) or …