How bacterial chemotaxis is performed is much better understood than why. Traditionally,
chemotaxis has been understood as a foraging strategy by which bacteria enhance their …

Networks of molecular regulators are often the primary objects of focus in the study of gene
regulation, with the machinery of protein synthesis tacitly relegated to the background …

Heterotrophic bacteria—bacteria that utilize organic carbon sources—are taxonomically and
functionally diverse across environments. It is challenging to map metabolic interactions and …

As a frequent inhabitant of sites polluted with toxic chemicals, the soil bacterium and plant-
root colonizer Pseudomonas putida can tolerate high levels of endogenous and exogenous …

Timely adaptation to nutrient downshift is crucial for bacteria to maintain fitness during feast
and famine cycle in the natural niche. However, the molecular mechanism that ensures the …

Evolution of complex communities of coexisting microbes remains poorly understood. The
long-term evolution experiment on Escherichia coli (LTEE) revealed the spontaneous …

Pseudomonas aeruginosa, a leading cause of severe hospital-acquired pneumonia, causes
infections with up to 50% mortality rates in mechanically ventilated patients. Despite some …

Efficient colonization of mucosal surfaces is essential for opportunistic pathogens like
Pseudomonas aeruginosa, but how bacteria collectively and individually adapt to optimize …

To respond to fluctuating conditions, microbes typically need to synthesize novel proteins.
As this synthesis relies on sufficient biosynthetic precursors, microbes must devise effective …

Bacterial fitness depends on adaptability to changing environments. In rich growth medium,
which is replete with amino acids, Escherichia coli primarily expresses protein synthesis …