Antibiotics are the commonest cause of life-threatening immune-mediated drug reactions
that are considered off-target, including anaphylaxis, and organ-specific and severe …

Abstract Background Even though 8%‐25% of most populations studied globally are labeled
as penicillin allergic, most diagnoses of penicillin allergy are made in childhood and relate …

Objective To evaluate the relation between penicillin allergy and development of meticillin
resistant Staphylococcus aureus (MRSA) and C difficile. Design Population based matched …

Background Reported penicillin allergy rarely reflects penicillin intolerance. Failure to
address inpatient penicillin allergies results in more broad-spectrum antibiotic use, treatment …

Background Patients who report a penicillin (PCN) allergy receive suboptimal antibiotic
therapy compared with patients not reporting an allergy. However, a majority of patients who …

Background Despite the high prevalence of patient-reported antibiotic allergy (so-called
antibiotic allergy labels [AALs]) and their impact on antibiotic prescribing, incorporation of …

Background Patients hospitalized with hematologic malignancy are particularly vulnerable
to infection. The impact of reported beta-lactam (BL) allergy in this population remains …

Background Having a penicillin allergy label is associated with the use of less appropriate
and more expensive antibiotics and increased healthcare utilization. Penicillin allergy …

Antibiotic allergy labeling is highly prevalent and negatively impacts patient outcomes and
antibiotic appropriateness. Reducing the prevalence and burden of antibiotic allergies …

Background Self-reported antibiotic allergies are common among hospitalized adults and
children. However, there is a paucity of studies investigating the impact of an antibiotic …