Machine learning for biomarker identification in cancer research–developments toward its clinical application

Z Jagga, D Gupta - Personalized medicine, 2015 - Taylor & Francis
The patterns identified from the systematically collected molecular profiles of patient tumor
samples, along with clinical metadata, can assist personalized treatments for effective …

[HTML][HTML] Integration of machine learning and meta-analysis identifies the transcriptomic bio-signature of mastitis disease in cattle

S Sharifi, A Pakdel, M Ebrahimi, JM Reecy… - PLoS one, 2018 - journals.plos.org
Gram-negative bacteria such as Escherichia coli (E. coli) are assumed to be among the
main agents that cause severe mastitis disease with clinical signs in dairy cattle. Rapid …

End-to-end interpretable disease–gene association prediction

Y Li, Z Guo, K Wang, X Gao… - Briefings in bioinformatics, 2023 - academic.oup.com
Identifying disease–gene associations is a fundamental and critical biomedical task towards
understanding molecular mechanisms, the diagnosis and treatment of diseases. It is time …

[HTML][HTML] Systematic enrichment analysis of microRNA expression profiling studies in endometriosis

S Wei, H Xu, Y Kuang - Iranian journal of basic medical sciences, 2015 - ncbi.nlm.nih.gov
Objective (s): The purpose of this study was to conduct a meta-analysis on human
microRNAs (miRNAs) expression data of endometriosis tissue profiles versus those of …

[HTML][HTML] Ranking candidate disease genes from gene expression and protein interaction: a Katz-centrality based approach

J Zhao, TH Yang, Y Huang, P Holme - PloS one, 2011 - journals.plos.org
Many diseases have complex genetic causes, where a set of alleles can affect the
propensity of getting the disease. The identification of such disease genes is important to …

Classifying processes: an essay in applied ontology

B Smith - Classifying Reality, 2013 - Wiley Online Library
We begin by describing recent developments in the burgeoning discipline of applied
ontology, focusing especially on the ways ontologies are providing a means for the …

[HTML][HTML] A multi-objective gene clustering algorithm guided by apriori biological knowledge with intensification and diversification strategies

J Parraga-Alava, M Dorn, M Inostroza-Ponta - BioData mining, 2018 - Springer
Background Biologists aim to understand the genetic background of diseases, metabolic
disorders or any other genetic condition. Microarrays are one of the main high-throughput …

Prediction of key regulators and downstream targets of E. coli induced mastitis

S Sharifi, A Pakdel, E Ebrahimie, Y Aryan… - Journal of applied …, 2019 - Springer
Mastitis, an inflammatory response of mammary glands to invading bacteria, is one of the
most economically costly diseases affecting dairy animals. Escherichia coli can be …

Biogeography-based informative gene selection and cancer classification using SVM and random forests

S Nikumbh, S Ghosh… - 2012 IEEE Congress on …, 2012 - ieeexplore.ieee.org
Microarray cancer gene expression data comprise of very high dimensions. Reducing the
dimensions helps in improving the overall analysis and classification performance. We …

[PDF][PDF] A Semantic Approach for Extracting Medical Association Rules.

M Thamer, S El-Sappagh, T El-Shishtawy - International Journal of …, 2020 - inass.org
Healthcare sector has large amounts of data that require careful analysis in order to improve
the medical service offered to the patients. Semantic data mining can play an effective rule in …