Gut Microbiome Integration in Drug Discovery and Development of Small Molecules

P Jimonet, C Druart, S Blanquet-Diot, L Boucinha… - Drug Metabolism and …, 2024 - ASPET
Human microbiomes, particularly in the gut, could have a major impact on the efficacy and
toxicity of drugs. However, gut microbial metabolism is often neglected in the drug discovery …

Investigation of Freezing and Freeze-Drying for Preserving and Re-Using a Whole Microbial Cheese Community

W Cao, S Passot, F Irlinger, F Fonseca - Foods, 2024 - mdpi.com
Preserving microbial ecosystems obtained from traditional cheese-making processes is
crucial to safeguarding the biodiversity of microbial cheese communities and thus ensuring …

Dynamic Monitoring of Changes in Fecal Flora of Giant Pandas in Mice: Co-Occurrence Network Reconstruction

B Gan, N Sun, J Lai, Z Wan, L Li, Y Wang… - Microbiology …, 2023 - Am Soc Microbiol
Giant pandas are uniquely vulnerable mammals in western China. It is important to develop
an animal model to explore the intestinal flora of giant pandas to understand the relationship …

Freeze-dried fecal microorganisms as an effective biomaterial for the treatment of calves suffering from diarrhea

T Nochi, J Islam, N Ohtani, Y Shimizu, M Tanimizu… - 2024 - researchsquare.com
Fecal microbiota transplantation (FMT) is a therapeutic modality for treating neonatal calf
diarrhea. Several practical barriers, including donor selection, fecal collection, and a limited …