Cancer nanotechnology: current status and perspectives

JA Kemp, YJ Kwon - Nano convergence, 2021 - Springer
Modern medicine has been waging a war on cancer for nearly a century with no tangible
end in sight. Cancer treatments have significantly progressed, but the need to increase …

[HTML][HTML] Current approaches of nanomedicines in the market and various stage of clinical translation

X Shan, X Gong, J Li, J Wen, Y Li, Z Zhang - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Compared with traditional drug therapy, nanomedicines exhibit intriguing biological features
to increase therapeutic efficiency, reduce toxicity and achieve targeting delivery. This review …

Bioengineered bacteria-derived outer membrane vesicles as a versatile antigen display platform for tumor vaccination via Plug-and-Display technology

K Cheng, R Zhao, Y Li, Y Qi, Y Wang, Y Zhang… - Nature …, 2021 - nature.com
An effective tumor vaccine vector that can rapidly display neoantigens is urgently needed.
Outer membrane vesicles (OMVs) can strongly activate the innate immune system and are …

Nanocarriers based on bacterial membrane materials for cancer vaccine delivery

X Zhao, R Zhao, G Nie - Nature protocols, 2022 - nature.com
Here we present a protocol for the construction and use of two types of nanocarrier based on
bacterial membrane materials for cancer vaccine delivery. Cancer vaccines induce tumor …

Engineered bacterial outer membrane vesicles as controllable two‐way adaptors to activate macrophage phagocytosis for improved tumor immunotherapy

Q Feng, X Ma, K Cheng, G Liu, Y Li, Y Yue… - Advanced …, 2022 - Wiley Online Library
The most immune cells infiltrating tumor microenvironment (TME), tumor‐associated
macrophages (TAMs) closely resemble immunosuppressive M2‐polarized macrophages …

Bacterial outer membrane vesicles as a platform for biomedical applications: An update

M Li, H Zhou, C Yang, Y Wu, X Zhou, H Liu… - Journal of Controlled …, 2020 - Elsevier
Outer membrane vesicles (OMVs) are produced by Gram-negative bacteria both in vitro and
in vivo. OMVs are nano-sized spherical vehicles formed by lipid bilayer membranes and …

Biomimetic nanotechnology toward personalized vaccines

J Zhou, AV Kroll, M Holay, RH Fang… - Advanced …, 2020 - Wiley Online Library
While traditional approaches for disease management in the era of modern medicine have
saved countless lives and enhanced patient well‐being, it is clear that there is significant …

Biomaterial-assisted biotherapy: A brief review of biomaterials used in drug delivery, vaccine development, gene therapy, and stem cell therapy

X Han, A Alu, H Liu, Y Shi, X Wei, L Cai, Y Wei - Bioactive Materials, 2022 - Elsevier
Biotherapy has recently become a hotspot research topic with encouraging prospects in
various fields due to a wide range of treatments applications, as demonstrated in preclinical …

Emerging biomaterials for tumor immunotherapy

M Xiao, Q Tang, S Zeng, Q Yang, X Yang… - Biomaterials …, 2023 - spj.science.org
Background The immune system interacts with cancer cells in various intricate ways that can
protect the individual from overproliferation of cancer cells; however, these interactions can …

[HTML][HTML] Extracellular vesicles: emerging tools as therapeutic agent carriers

S Liu, X Wu, S Chandra, C Lyon, B Ning, J Fan… - … Pharmaceutica Sinica B, 2022 - Elsevier
Extracellular vesicles (EVs) are secreted by both eukaryotes and prokaryotes, and are
present in all biological fluids of vertebrates, where they transfer DNA, RNA, proteins, lipids …