Chemokines are chemotactic cytokines that control the migration and positioning of immune
cells in tissues and are critical for the function of the innate immune system. Chemokines …

Chemokines are chemo tactic cyto kines that control the migratory patterns and positioning
of all immune cells. Although chemokines were initially appreciated as important mediators …

Abstract Dipeptidyl peptidase-4 (DPP4) is a widely expressed enzyme transducing actions
through an anchored transmembrane molecule and a soluble circulating protein. Both …

Short chain fatty acids (SCFAs), including acetate, propionate, and butyrate, are produced at
high concentration by bacteria in the gut and subsequently released in the bloodstream …

Post-translational modification of chemokines mediated by the dipeptidyl peptidase DPP4
(CD26) has been shown to negatively regulate lymphocyte trafficking, and its inhibition …

Dipeptidyl-peptidase IV (DPP IV/CD26) has a dual function as a regulatory protease and as
a binding protein. Its role in the inactivation of bioactive peptides was recognized 20 years …

Chemokines are the largest family of cytokines in human immunophysiology. These proteins
are defined by four invariant cysteines and are categorized based on the sequence around …

CD26/DPPIV can be considered a moonlighting protein because it is a multifunctional
protein that exerts its different functions depending on cell type and intra-or extracellular …

Healthy individuals initiate an immediate immune response to microbes by using a set of
germline-encoded receptors that recognize common molecular patterns found on the …

CD26 has proved interesting in the fields of immunology, endocrinology, cancer biology and
nutrition owing to its ubiquitous and unusual enzyme activity. This dipeptidyl …