Brain stimulation techniques offer powerful means of modulating the physiology of specific
neural structures. In recent years, non-invasive brain stimulation techniques, such as …

Objective Real-world evidence in treatment-resistant depression (TRD; commonly defined
as non-response to≥ 2 consecutive treatments at adequate dosage and duration) is lacking …

Resistance to pharmacological treatment poses a notable challenge for psychiatry. Such
cases are usually treated with brain stimulation techniques, including repetitive transcranial …

Background: Although the antidepressant potential of repetitive transcranial magnetic
stimulation (rTMS), the pleiotropic effects in geriatric depression (GD) are poorly …

Major depressive disorder is a leading cause of disability worldwide and a major contributor
to the overall global burden of disease. While there are several options for antidepressant …

Background: in a recent double-blind, placebo controlled RCT we demonstrated that
selective inhibition of cyclo-oxygenase 2 (COX2) is an effective adjunctive strategy in …

Alzheimer's disease is a neurodegenerative disease resulting from deficits in synaptic
transmission and homeostasis. The Alzheimer's disease brain tends to be hyperexcitable …

Zusammenfassung Zur Neurobiologie der therapieresistenten Depression (TRD) gibt es
erstaunlich wenig robuste Befunde, was methodische Gründe hat, aber auch an der …

Introduction: TMS and EEG are used to study normal neurophysiology, diagnose, and treat
clinical neuropsychiatric conditions, but can produce variable results or fail. Both techniques …

A major depresszív zavar (MD) jelentős szenvedést okozó, időtartamában gyakran elhúzódó
negatív hangulati, érzelmi és kognitív panaszokkal járó mentális zavar. Nem ritkán krónikus …