Fluorosis is a major public health problem globally. The non-availability of specific treatment
and the irreversible nature of dental and skeletal lesions poses a challenge in the …

Fluoride is a natural element essential in minute quantities in human's to maintain dental
and skeletal health. However, the disease fluorosis manifests itself due to excessive fluoride …

Long-term exposure to high concentrations of fluoride (F) can damage mineralized and soft
tissues such as bones, liver, kidney, intestine, and nervous system of adult rats. The high …

An extensive body of research has demonstrated that pulmonary toxicity induced by fluoride
is related to cell apoptosis. Although induction of death receptor-initiated extrinsic apoptosis …

Free radicals and other oxidants have enticed the interest of researchers in the fields of
biology and medicine, owing to their role in several pathophysiological conditions, including …

Background The skeletal muscle of pigs is vulnerable to oxidative damage, resulting in
growth retardation. Selenoproteins are important components of antioxidant systems for …

Toxicity caused by chronic hyperglycemia is a significant factor affecting skeletal muscle
myogenesis, resulting in diabetic myopathy. Chronic and persistent hyperglycemia causes …

Excess intake of fluoride leads to a serious health issue called fluorosis. Fluorosis patients
exhibit the symptom of muscle damage, but the specific mechanism remains unclear …

Fluoride at high doses is a well-known toxic agent for the musculoskeletal system, primarily
in bone and cartilage cells. Research on fluoride toxicity concerning particularly on the …

Introduction Fluoride is considered an environmental pollutant that seriously affects
organisms and ecosystems, and its harmfulness is a perpetual public health concern. The …