Highlights•Metaplasticity phenomena underlie the state-dependency of synaptic
plasticity.•Activation and trafficking of glutamate receptors underpin metaplasticity …

Reconsolidation, a process by which long-term memories are rendered malleable following
retrieval, has been shown to occur across many different species and types of memory …

Exposure to environmental enrichment can beneficially influence the behavior and enhance
synaptic plasticity. The aim of the present study was to investigate the mediated effects of …

The neurobiological processes underpinning the natural forgetting of long-term memories
are poorly understood. Based on the critical role of GluA2-containing AMPA receptors …

In the past decades, the cellular and molecular mechanisms underlying memory
consolidation, reconsolidation, and extinction have been well characterized. However, the …

Osmanthus fragrans flower extract (OFE) is an organic extract from O. fragrans flower, which
exhibits neuroprotective, free radical scavenging, and antioxidant effects. Therefore, the …

Diisononyl phthalate (DINP) is a plasticizer that is frequently used as a substitute for other
plasticizers whose use is prohibited in certain products. In vivo studies on the neurotoxicity …

Episodic memory is essential to navigate in a changing environment by recalling past
events, creating new memories, and updating stored information from experience. Although …

The time‐dependent forgetting of long‐term spatial memories involves activation of NMDA
receptors (NMDARs) in the hippocampus. Here, we tested whether NMDARs regulate …

The hippocampus is a key brain area to encoding and storing memories. Hippocampal
place cells encode the position of an animal in space by firing when the subject is at a …