Pharmaceutical cocrystal of antibiotic drugs: A comprehensive review

M Bashimam, H El-Zein - Heliyon, 2022 - cell.com
Pharmaceutical cocrystals, which contain at least one active pharmaceutical ingredient
(API), are still an attention-grabbing field for researchers. Two or more discrete molecules …

Cocrystal of ibuprofen–nicotinamide: solid-state characterization and in vivo analgesic activity evaluation

Y Yuliandra, E Zaini, S Syofyan, W Pratiwi… - Scientia …, 2018 - mdpi.com
Ibuprofen is classified as a BCS class II drug which has low solubility and high permeability.
We conducted the formation of the cocrystalline phase of ibuprofen with coformer …

Hansen solubility parameters and green nanocarrier based removal of trimethoprim from contaminated aqueous solution

O Afzal, HA Alshammari, MA Altamimi… - Journal of Molecular …, 2022 - Elsevier
The study aimed to address efficient and safe green nanoemulsions (NE) to remove
Trimethoprim (TMT) contaminated water using water/cremophor EL/propylene …

Green nanoemulsion-based treatment to remove sulfamethoxazole from a contaminated water solution

A Hussain, MA Altamimi, SS Imam, F Imam - Journal of Molecular Liquids, 2023 - Elsevier
Sulfamethoxazole (SUX) is a common pharmaceutical, but represents a potential global
threat to human health due to its exhaustive use and consequent outflow in the environment …

[PDF][PDF] Enhancing solubility and antibacterial activity using multicomponent crystals of trimethoprim and malic acid

Y Yuliandra, LJ Hutabarat, R Ardila, MD Octavia… - Pharm …, 2021 - researchgate.net
Aim: To improve the solubility and antibacterial activity of trimethoprim (TMP) by preparing its
multicomponent crystals with malic acid (MA). Methods: Multicomponent crystals of TMP-MA …

Synthesis and antibacterial evaluation of new azo-pyrimidine derivatives

MA Abdelgawad - Journal of Applied Pharmaceutical Science, 2019 - japsonline.com
The synthesis of potent antibacterial agents, free from side effects and resistant to bacterial
enzymes, is the main objective for drug designers. Also, the multi-target drugs have an …

[PDF][PDF] Trimethoprim determination with drug-selective electrodes

SA Abrahem, AM Abass, A Ahmed - Asian J Pharm Clin Res, 2019 - researchgate.net
Developed ion-selective electrode has been industrialized for the determination of
trimethoprim (TMP) in pure form and pharmaceutical preparations. The selective electrode …

Optimized Green Nanoemulsions to Remove Pharmaceutical Enoxacin from Contaminated Bulk Aqueous Solution

A Hussain, SS Imam, MA Altamimi, M Shahid… - ACS …, 2023 - ACS Publications
We attempted to develop green nanoemulsions (ENE1–ENE5) using capryol-C90 (C90),
lecithin, Tween 80, and N-methyl-2-pyrrolidone (NMP). HSPiP software and experimentally …

Multicomponent Crystals of Piperine-Nicotinic Acid: The Physicochemical and Dissolution Rate Properties.

MD Octavia, H Hasmiwati, G Revilla… - Tropical Journal of …, 2023 - search.ebscohost.com
Piperine is included in Class II of the Biopharmaceutical Classification System. Piperine has
low solubility in water, resulting in low bioavailability. To improve the physicochemical …

Multicomponent crystal of trimethoprim and citric acid: solid state characterization and dissolution rate studies

S Umar, R Farnandi, H Salsabila, E Zaini - Open Access Macedonian …, 2022 - oamjms.eu
BACKGROUND: Trimethoprim is a broad spectrum antimicrobial agent with low solubility in
water which causes low bioavailability in systemic circulation. AIM: The purpose of this study …