Bacterial outer membrane vesicles: from discovery to applications

MG Sartorio, EJ Pardue, MF Feldman… - Annual review of …, 2021 - annualreviews.org
Secretion of cellular components across the plasma membrane is an essential process that
enables organisms to interact with their environments. Production of extracellular vesicles in …

Outer membrane vesicles: biogenesis, functions, and issues

R Juodeikis, SR Carding - Microbiology and Molecular Biology …, 2022 - Am Soc Microbiol
This review focuses on nonlytic outer membrane vesicles (OMVs), a subtype of bacterial
extracellular vesicles (BEVs) produced by Gram-negative organisms focusing on the …

Extracellular vesicles as a novel mediator of interkingdom communication

J Huang, X Wang, Z Wang, L Deng, Y Wang… - Cytokine & Growth …, 2023 - Elsevier
Extracellular vesicles (EVs) are nanosized lipid bilayer-delimited particles secreted from
almost all types of cells including bacteria, mammals and plants, and are presumed to be …

Engineered bacterial membrane vesicles are promising carriers for vaccine design and tumor immunotherapy

Q Long, P Zheng, X Zheng, W Li, L Hua, Z Yang… - Advanced drug delivery …, 2022 - Elsevier
Bacterial membrane vesicles (BMVs) have emerged as novel and promising platforms for
the development of vaccines and immunotherapeutic strategies against infectious and …

OMV vaccines and the role of TLR agonists in immune response

F Mancini, O Rossi, F Necchi, F Micoli - International journal of molecular …, 2020 - mdpi.com
Outer Membrane Vesicles (OMVs) are bacterial nanoparticles that are spontaneously
released during growth both in vitro and in vivo by Gram-negative bacteria. They are …

Membrane vesicle production as a bacterial defense against stress

N Mozaheb, MP Mingeot-Leclercq - Frontiers in microbiology, 2020 - frontiersin.org
Membrane vesicles are the nano-sized vesicles originating from membranes. The
production of membrane vesicles is a common feature among bacteria. Depending on the …

Outer membrane lipid secretion and the innate immune response to gram-negative bacteria

NP Giordano, MB Cian, ZD Dalebroux - Infection and immunity, 2020 - Am Soc Microbiol
The outer membrane (OM) of Gram-negative bacteria is an asymmetric lipid bilayer that
consists of inner leaflet phospholipids and outer leaflet lipopolysaccharides (LPS). The …

Bacterial membrane vesicle functions, laboratory methods, and applications

PA Çelik, B Derkuş, K Erdoğan, D Barut… - Biotechnology …, 2022 - Elsevier
Bacterial membrane vesicles (BMVs) are cupped-shaped structures formed by bacteria in
response to environmental stress, genetic alteration, antibiotic exposure, and others. Due to …

[HTML][HTML] Bacterial extracellular vesicle applications in cancer immunotherapy

K Suri, A D'Souza, D Huang, A Bhavsar, M Amiji - Bioactive Materials, 2023 - Elsevier
Cancer therapy is undergoing a paradigm shift toward immunotherapy focusing on various
approaches to activate the host immune system. As research to identify appropriate immune …

Immunomodulatory roles and novel applications of bacterial membrane vesicles

WJ Gilmore, EL Johnston, L Zavan, NJ Bitto… - Molecular …, 2021 - Elsevier
Bacteria release extracellular vesicles (EVs) known as bacterial membrane vesicles (BMVs)
during their normal growth. Gram-negative bacteria produce BMVs termed outer membrane …