Abnormal cell metabolism with vigorous nutrition consumption is one of the major
physiological characteristics of cancers. As such, the strategy of cancer starvation therapy …

Perfluorooctylbromide nanoparticles (PFOB NPs) are a type of multifunctional
nanotechnology that has been studied for various medical applications. Commercial …

Tumor-associated macrophages (TAMs) enhance tumor growth in mice and are correlated
with a worse prognosis for breast cancer patients. While early therapies sought to deplete all …

The first developed secretory phospholipase A 2 (sPLA 2) sensitive liposomal cisplatin
formulation (LiPlaCis®) is currently undergoing clinical evaluation. In the present study we …

The success of any given cancer immunotherapy relies on several key factors. In particular,
success hinges on the ability to stimulate the immune system in a controlled and precise …

Breast cancer bone metastases are common and incurable. Tumoral integrin β3 (β3)
expression is induced through interaction with the bone microenvironment. Although β3 is …

The rabbit VX2 is a large animal model of cancer used for decades by interventional
radiologists to demonstrate the efficacy of various locoregional treatments against liver …

Methionine aminopeptidases (MetAPs) have emerged as a target for medicinal chemists in
the quest for novel therapeutic agents for treating cancer, obesity, and other disorders …

Rationale: Multiple myeloma (MM) is a multifocal malignancy of bone marrow plasma cells,
characterized by vicious cycles of remission and relapse that eventually culminate in death …

Although angiogenesis is a hallmark feature of asthmatic inflammatory responses,
therapeutic anti-angiogenesis interventions have received little attention. Objective: Assess …