Cancer diseases have been one of the biggest health threats for the last two decades.
Approximately 9% of all diagnosed cancers are skin cancers, including melanoma and non …

Skin in vitro models offer much promise for research, testing drugs, cosmetics, and medical
devices, reducing animal testing and extensive clinical trials. There are several in vitro …

Melanoma is a life-threatening disease due to the early onset of metastasis and frequent
resistance to the applied treatment. For now, no single histological, immunohistochemical or …

Background Melanoblasts originate in the neural crest from where they migrate to peripheral
tissues and differentiate into melanocytes. Alteration during melanocyte development and …

Various in vitro three-dimensional (3D) tissue culture models of human and diseased skin
exist. Nevertheless, there is still room for the development and improvement of 3D bioprinted …

Simple Summary Anandamide (AEA) belongs to the group of endocannabinoids and
possesses various regulatory properties in physiological as well as pathological processes …

We developed novel and optimal Q10-NLC/SLN formulations as antioxidant and anti-
tyrosinase agents. The formulations were analyzed for particle size, morphology, entrapment …

Melanoma is a very aggressive, rapidly metastasizing tumor that has been studied
intensively in the past regarding the underlying genetic and molecular mechanisms. More …

Background: Tazarotene (TZ) is a novel acetylenic class retinoid that selectively targets
RARβ/γ. It is not particularly soluble or bioavailable, yet it is used to treat melanoma …

Human skin melanocytes, consisting of ca. 3–7% of all epidermal cells, are indispensable
for the synthesis of melanin during a multistep process called melanogenesis, determining …