Regulation of sexually dimorphic expression of major urinary proteins

DJ Penn, SM Zala, KC Luzynski - Frontiers in Physiology, 2022 - frontiersin.org
Male house mice excrete large amounts of protein in their urinary scent marks, mainly
composed of Major Urinary Proteins (MUPs), and these lipocalins function as pheromones …

Update on the human and mouse lipocalin (LCN) gene family, including evidence the mouse Mup cluster is result of an “evolutionary bloom”

G Charkoftaki, Y Wang, M McAndrews, EA Bruford… - Human genomics, 2019 - Springer
Lipocalins (LCNs) are members of a family of evolutionarily conserved genes present in all
kingdoms of life. There are 19 LCN-like genes in the human genome, and 45 Lcn-like genes …

A novel role for subcutaneous adipose tissue in exercise-induced improvements in glucose homeostasis

KI Stanford, RJW Middelbeek, KL Townsend… - Diabetes, 2015 - Am Diabetes Assoc
Exercise training improves whole-body glucose homeostasis through effects largely
attributed to adaptations in skeletal muscle; however, training also affects other tissues …

[HTML][HTML] The vomeronasal organ mediates interspecies defensive behaviors through detection of protein pheromone homologs

F Papes, DW Logan, L Stowers - Cell, 2010 - cell.com
Potential predators emit uncharacterized chemosignals that warn receiving species of
danger. Neurons that sense these stimuli remain unknown. Here we show that detection and …

Long‐term therapeutic silencing of miR‐33 increases circulating triglyceride levels and hepatic lipid accumulation in mice

L Goedeke, A Salerno, CM Ramírez, L Guo… - EMBO molecular …, 2014 - embopress.org
Plasma high‐density lipoprotein (HDL) levels show a strong inverse correlation with
atherosclerotic vascular disease. Previous studies have demonstrated that antagonism of …

Maternal exercise improves glucose tolerance in female offspring

KI Stanford, H Takahashi, K So, AB Alves-Wagner… - Diabetes, 2017 - Am Diabetes Assoc
Poor maternal diet can lead to metabolic disease in offspring, whereas maternal exercise
may have beneficial effects on offspring health. In this study, we determined ifmaternal …

[PDF][PDF] Liver‐specific loss of glucose‐regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in mice

C Ji, N Kaplowitz, MY Lau, E Kao, LM Petrovic… - …, 2011 - Wiley Online Library
The endoplasmic reticulum (ER) chaperone protein glucose‐regulated protein 78
(GRP78)/binding immunoglobulin protein is a master regulator of ER homeostasis and …

Metabolic changes and propensity for inflammation, fibrosis, and cancer in livers of mice lacking lysosomal acid lipase

I Bradić, L Liesinger, KB Kuentzel, N Vujić… - Journal of Lipid …, 2023 - ASBMB
Lysosomal acid lipase (LAL) is the sole lysosomal enzyme responsible for the degradation
of cholesteryl esters and triacylglycerols at acidic pH. Impaired LAL activity leads to LAL …

Integrative transcriptomics and metabolomics explore the mechanism of kaempferol on improving nonalcoholic steatohepatitis

Y Lu, M Shao, H Xiang, P Zheng, T Wu, G Ji - Food & function, 2020 - pubs.rsc.org
Kaempferol has been confirmed to be effective in improving metabolic diseases such as
diabetes and obesity. However, its effect and mechanism in nonalcoholic steatohepatitis …

Follistatin promotes adipocyte differentiation, browning, and energy metabolism [S]

M Braga, ST Reddy, L Vergnes, S Pervin… - Journal of lipid …, 2014 - ASBMB
Follistatin (Fst) functions to bind and neutralize the activity of members of the transforming
growth factor-β superfamily. Fst has a well-established role in skeletal muscle, but we …