A large number of genes associated with various cancer types contain single nucleotide
polymorphisms (SNPs). SNPs are located in gene promoters, exons, introns as well as 5' …

Matrix metalloproteinases (MMPs) are a large family of zinc-endopeptidases which play
important roles in multiple physiological and pathological processes. These enzymes are …

[Frontiers in Bioscience 11, 479-491, January 1, 2006] 479 Matrix metalloproteinases: roles in
cancer and metastasis Barbara Fin Page 1 [Frontiers in Bioscience 11, 479-491, January 1 …

Background & Aims: Overexpression of cyclooxygenase-2 (COX-2) is implicated in many
steps of cancer development. Single nucleotide polymorphisms (SNPs) in the COX-2 …

Extracellular matrix (ECM) remodeling is crucial in the regulation of gastric cancer (GC)
progression. This work aims to reveal novel posttranslational modifications and their …

MMP-2 and MMP-9 genes have been suggested to play a role in breast cancer. Their
functions have been associated with invasion and metastasis of breast cancer; however …

The aim of this paper is to review and evaluate, in a comprehensive manner, the published
data regarding the contribution of genetic polymorphisms to risk of esophageal cancer …

The tumor suppressor P53 pathway plays a crucial role in preventing carcinogenesis and
genetic variations of this pathway may be associated with cancer susceptibility. We tested …

Abstract Background. Matrix metalloproteinases (MMPs) and transforming growth factor‐β1
(TGF‐β1) are important in many physiological and pathological processes. Methods …

Lung cancer is one of the most common and deadliest cancers in the world. The major socio-
environmental risk factor involved in the development of lung cancer is cigarette smoking …