Human pathogens and the host cell SUMOylation system
P Wimmer, S Schreiner, T Dobner - Journal of virology, 2012 - Am Soc Microbiol
Since posttranslational modification (PTM) by the small ubiquitin-related modifiers (SUMOs)
was discovered over a decade ago, a huge number of cellular proteins have been found to …
was discovered over a decade ago, a huge number of cellular proteins have been found to …
Hacking the cell: network intrusion and exploitation by adenovirus E1A
As obligate intracellular parasites, viruses are dependent on their infected hosts for survival.
Consequently, viruses are under enormous selective pressure to utilize available cellular …
Consequently, viruses are under enormous selective pressure to utilize available cellular …
Poly-small ubiquitin-like modifier (PolySUMO)-binding proteins identified through a string search
Polysumoylation is a crucial cellular response to stresses against genomic integrity or
proteostasis. Like the small ubiquitin-like modifier (SUMO)-targeted ubiquitin ligase RNF4 …
proteostasis. Like the small ubiquitin-like modifier (SUMO)-targeted ubiquitin ligase RNF4 …
Superior infectivity of the fiber chimeric oncolytic adenoviruses Ad5/35 and Ad5/3 over Ad5-delta-24-RGD in primary glioma cultures
AA Stepanenko, AO Sosnovtseva, MP Valikhov… - Molecular Therapy …, 2022 - cell.com
Ad5-delta-24-RGD is currently the most clinically advanced recombinant adenovirus (rAd)
for glioma therapy. We constructed a panel of fiber-modified rAds (Ad5RGD, Ad5/3, Ad5/35 …
for glioma therapy. We constructed a panel of fiber-modified rAds (Ad5RGD, Ad5/3, Ad5/35 …
Adenovirus E1B-55K controls SUMO-dependent degradation of antiviral cellular restriction factors
The human adenovirus species C type 5 (HAdV-C5) early region 1B 55 kDa (E1B-55K)
protein is a multifunctional protein that promotes viral replication and adenovirus-mediated …
protein is a multifunctional protein that promotes viral replication and adenovirus-mediated …
Viral manipulation of the cellular sumoylation machinery
AJ Lowrey, W Cramblet, GL Bentz - Cell Communication and Signaling, 2017 - Springer
Viruses exploit various cellular processes for their own benefit, including counteracting anti-
viral responses and regulating viral replication and propagation. In the past 20 years, protein …
viral responses and regulating viral replication and propagation. In the past 20 years, protein …
Sp100 isoform-specific regulation of human adenovirus 5 gene expression
Promyelocytic leukemia nuclear bodies (PML-NBs) are nuclear structures that accumulate
intrinsic host factors to restrict viral infections. To ensure viral replication, these must be …
intrinsic host factors to restrict viral infections. To ensure viral replication, these must be …
Viral DNA binding protein SUMOylation promotes PML nuclear body localization next to viral replication centers
M Stubbe, J Mai, C Paulus, HC Stubbe… - MBio, 2020 - Am Soc Microbiol
Human adenoviruses (HAdVs) have developed mechanisms to manipulate cellular antiviral
measures to ensure proper DNA replication, with detailed processes far from being …
measures to ensure proper DNA replication, with detailed processes far from being …
A tale of usurpation and subversion: SUMO-dependent integrity of promyelocytic leukemia nuclear bodies at the crossroad of infection and immunity
Promyelocytic leukemia nuclear bodies (PML NBs) are multi-protein assemblies
representing distinct sub-nuclear structures. As phase-separated molecular condensates …
representing distinct sub-nuclear structures. As phase-separated molecular condensates …
Cross-talk between phosphorylation and SUMOylation regulates transforming activities of an adenoviral oncoprotein
P Wimmer, P Blanchette, S Schreiner, W Ching, P Groitl… - Oncogene, 2013 - nature.com
Since the discovery of post-translational modification (PTM) by the small ubiquitin-related
modifiers (SUMOs), a multitude of proteins have been described to be reversibly modified …
modifiers (SUMOs), a multitude of proteins have been described to be reversibly modified …